Results 91 to 100 of about 2,200 (151)

Clonal Hematopoiesis and Therapy-Related Myeloid Neoplasms After Autologous Transplant for Hodgkin Lymphoma. [PDF]

J Clin Oncol
Yan C, Richard MA, Gibson CJ, He J, Bosworth A, Crossman DK, Singh P, Hageman L, Kalra R, Armenian SH, Vose J, Weisdorf DJ, Ebert BL, Yasui Y, Forman SJ, Bhatia R, Bhatia S.   +16 more
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Dysregulation of the mTOR pathway by mechlorethamine

Toxicology, 2023
Mechlorethamine (HN2) is a derivative of the chemical warfare agent sulfur mustard (SM) and cutaneous exposure to HN2 is associated with dermal-epidermal junction (DEJ) disruption (vesication). The primary purpose of the present study was to investigate the effect of HN2 on the mammalian target of rapamycin (mTOR) signaling pathway using an in vivo ...
Trishaal Janardhanam Raghavendra, Rao, Ganming, Mao, Benedette J, Cuffari, Blase, Billack   +3 more
openaire   +2 more sources

Local bullous reaction to topical mechlorethamine (mustine)

Contact Dermatitis, 1990
J J, Goday, A, Aguirre, J A, Ratón, J L, Díaz-Pérez   +3 more
exaly   +3 more sources

Hypersensitivity to Mechlorethamine

Annals of Internal Medicine, 1981
Excerpt To the editor: The recently published review by Weiss and Bruno (1) prompts us to report a second case of type 1 hypersensitivity to intravenous mechlorethamine.
KENNETH S. WILSON, SKARIA ALEXANDER
openaire   +1 more source

Accidental intramuscular injection of mechlorethamine

Cancer, 1980
A 55-year-old man with chronic, active diffuse psoriasis was accidentally given 30 mg of mechlorethmine deep into the buttock muscles. About 5 hours after the intramuscular (IM) mechlorethamine injection, 1/6 M sodium thiosulfate was infused around the intramuscular site.
O E, Owen, D L, Dellatorre, E J, Van Scott, M R, Cohen   +3 more
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Hyperbaric Oxygenation and Mechlorethamine Effectiveness

Archives of Surgery, 1963
In order to test one of the possible radiomimetic qualities of alkylating agents, we have studied the influence of hyperbaric oxygen on the tumoricidal action of mechlorethamine (nitrogen mustard) in spontaneous mammary tumors of heterozygous, randomly bred Swiss-Webster mice.
R P, LEATHER, C, ECKERT
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Mechlorethamine Hydrochloride

Archives of Surgery, 1964
The use of chemotherapeutic agents as an adjunct to operative management of malignant disease is receiving considerable attention in current cancer research. Since the effects of these highly toxic drugs are not entirely limited to neoplastic tissue, however, knowledge of their effects on normal healing of wounds would be valuable.
C G, LONGENECKER, E T, KREMENTZ
openaire   +2 more sources

Chemotherapy of Lymphoma With Mechlorethamine and Vinblastine

Archives of Internal Medicine, 1973
To determine the relative efficacy of mechlorethamine hydrochloride and vinblastine sulfate, 172 patients with Hodgkin's disease, lymphosarcoma, and reticulum cell sarcoma were randomly assigned to receive one or the other of these agents. If treatment with the first compound failed, each patient was to be treated with the second.
J, Solomon, E M, Jacobs, J R, Bateman, R J, Lukes, J M, Weiner, D M, Donohue   +5 more
openaire   +3 more sources

NMR studies of the conjugation of mechlorethamine with glutathione

Journal of Medicinal Chemistry, 1990
Many cancer cells are resistant to chemotherapeutic treatment with mechlorethamine and other alkylating agents. These drug-resistant cells often show an increase in the intracellular concentration of glutathione and an increase in the activity of glutathione-S-transferase when compared to the sensitive cells.
M P, Gamcsik, T G, Hamill, M, Colvin
openaire   +2 more sources