Results 81 to 90 of about 2,699 (183)
A Timecourse Based Dermatotoxicity Evaluation of Mechlorethamine on Damage and Repair Related Protein Expression in the Mouse Ear Vesicant Model [PDF]
Mechlorethamine (HN2) is a type of nitrogen mustard alkylating agent that has been widely applied as an anticancer drug. HN2 is an analog of the corrosive reagent sulfur mustard, which is highly reactive with skin and organisms exposed to HN2 develop ...
Mao, Ganming
core
We undertook a phase II study of combination chemotherapy with mechlorethamine (nitrogen mustard) 6 mg/m2 intravenously day 1 and day 8, vincristine 2 mg intravenously day 1 and day 8, and procarbazine 100 mg/m2 orally days 1 through 14 (MOP) in adults ...
T Coyle +9 more
core +1 more source
JEADV Clinical Practice, Volume 4, Issue 2, Page 552-555, June 2025.
Michelle Raaijmakers +5 more
wiley +1 more source
Objectives The goals of this retrospective study were to evaluate the use of mechlorethamine, vincristine, melphalan and prednisolone (MOMP) chemotherapy for rescue of feline lymphoma, to describe the protocol’s toxicity and to determine prognostic ...
Olya A Martin, Josh Price
core +1 more source
Therapeutic Options in Patients With Lymphoma and Severe Liver Dysfunction
To determine the long-term outcome of patients presenting with synchronous lymphoma and severe liver dysfunction and to describe the outcome of patients treated with initial mechlorethamine-based therapy used as a bridge to more conventional chemotherapy.
White, William L +12 more
core +1 more source
Influence of granulocytopenia on canine cerebral ischemia induced by air embolism.
We subjected nine dogs with severe granulocytopenia 4 days after the administration of mechlorethamine to 1 hour of cerebral ischemia induced by the controlled, incremental injection of air into the internal carotid artery.
A J Dutka, J M Hallenbeck, P M Kochanek
core +1 more source
Thirty-nine patients with advanced Hodgkin's disease were treated with doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD). Thirty-one of these patients had previously failed to respond to MOPP (mechlorethamine, vincristine, prednisone, and ...
TODESCHINI, Giuseppe +5 more
core +1 more source
A series of benzene-substituted analogues of the novel hypoxia-selective cytotoxin N,N-bis(2-chloroethyl)-N-methyl-N-(2-nitrobenzyl)ammonium chloride (3a), together with three corresponding tetrahydroisoquinolinium “cyclic” analogues 21a−23a and two ...
William R. Wilson (210146) +3 more
core +1 more source
The reaction of K2PtCl4 with anticancer-alkylating agent mechlorethamine hydrochloride (CH3NH(C2H4Cl)2 x HCl = HN2×HCl), in the molar ratio 1 : 2, affords the complex [H2N2] 2[PtCl4].
Čomić, Ljiljana +5 more
core +1 more source
Dose intensity of MOPP chemotherapy and survival in Hodgkin's disease.
The association between dose intensity of chemotherapy with the rate of complete remission (CR), the duration of disease-free survival (DFS), and overall survival (OS) was separately analyzed for 67 patients initially treated with mechlorethamine ...
A J de Meijer +4 more
core +1 more source

