Results 81 to 90 of about 2,545 (184)

The Mechanism of Guanine Alkylation by Nitrogen Mustards: A Computational Study

, 2012
The thermodynamics and kinetics for the monofunctional binding of nitrogen mustard class of anticancer drugs to purine bases of DNA were studied computationally using guanine and adenine as model substrates.
Stillabower, Jacob A., Polavarapu, Abhigna, Taylor, William M., Baik, Mu-Hyun, Stubblefield, Skyler G. W.   +4 more
core   +1 more source

EVALUATING THE EFFECTS OF MECHLORETHAMINE ON THE DERMAL-EPIDERMAL JUNCTION

, 2022
Sulfur Mustard (SM) is a chemical warfare agent first utilized on the battlefield more than 100 years ago. To the present time, no antidote to combat the dermatotoxicity of SM exists.
Janardhanam Raghavendra Rao, Trishaal
core  

Mechlorethamine gel usage in patients with mycosis fungoides in a lymphoma clinic

Indian Journal of Dermatology, 2020
Robert Duffy, Tara Jennings, Joya Sahu
doaj   +1 more source

Comparison of Individual Strain Analysis to Microarray Results

, 2013
(A) Representative growth curves of 16 individual strains grown in the presence of solvent alone (DMSO, red curve) and 62.5 μM mechlorethamine (black curve). Growth was monitored by measuring the optical density (OD600) of cultures every 15 min for 30 h.
Guri Giaever (42520), Michael I Jordan (51066), Corey Nislow (42521), Adam P Arkin (20027), Ronald W Davis (26604), William Lee (256063), Patrick Flaherty (54071), Robert P St.Onge (275012), Michael Proctor (275013)   +8 more
core   +1 more source

Effect of Alkylating Agents on the Clearance of Staphylococcus aureus From Murine Lungs

, 1987
Alkylating agents have several effects on cellular host defense responses which could increase either the frequency or the severity of pulmonary infections.
Kenneth M Nugent, John M Onofrio
core   +1 more source

The Mechanism of Guanine Alkylation by Nitrogen Mustards: A Computational Study

, 2016
The thermodynamics and kinetics for the monofunctional binding of nitrogen mustard class of anticancer drugs to purine bases of DNA were studied computationally using guanine and adenine as model substrates.
Skyler G. W. Stubblefield (2062453), William M. Taylor (114689), Abhigna Polavarapu (1872133), Mu-Hyun Baik (1466125), Jacob A. Stillabower (2062456)   +4 more
core   +1 more source

Evaluation and management of patients with early-stage mycosis fungoides who interrupt or discontinue topical mechlorethamine gel because of dermatitis

JAAD Case Reports, 2020
Elaine S. Gilmore, MD, PhD, Carolina V. Alexander-Savino, BS, Catherine G. Chung, MD, Brian Poligone, MD, PhD   +3 more
doaj   +1 more source

Experimental bronchial arterial infusion of mechlorethamine

The Journal of Thoracic and Cardiovascular Surgery, 1965
J B, MARK, R P, HOCKMAN, C B, CARRINGTON
openaire   +2 more sources

Sézary syndrome presenting as vitiligo-like leukoderma with response and repigmentation to mogamulizumab and extracorporeal photopheresis. [PDF]

JAAD Case Rep
Anderson E, Puccio J, Mou E, Swick B, Liu V.   +4 more
europepmc   +1 more source

Examination of a Chimeric Bis-Electrophile for Selective DNA-Protein Cross-Linking and Mechlorethamine Reveals an Unknown Source of Nitrogen Mustard Cytotoxicity. [PDF]

J Am Chem Soc
Jiang X, Vu S, Yu H, Greenberg MM.
europepmc   +1 more source