Results 61 to 70 of about 2,699 (183)
The schematic illustrates that corneal injury imparted by a stromal incision or by toxic chemical exposure causes corneal Schwann cells (cSCs) and axons to degenerate rapidly, resulting in impaired mechanosensory function. We hypothesized that repair cSCs, which develop post injury, are an as‐yet‐untested cellular target for axonal regeneration.
Michael Li +6 more
wiley +1 more source
HPLC has been applied to determine the stability of mechlorethamine hydrochloride (nitrogen mustard) formulated as an ointment in white soft paraffin (10 mg drug, 50 g paraffin and 1 mL acetone). A new solubilization technique is described for extraction
J F Smyth +3 more
core +1 more source
Caitlin Crimp,1 Ameya Gangal,2 Erica S Tarabadkar,3 Michi M Shinohara1,4 1Division of Dermatology, University of Washington, Seattle, WA, USA; 2School of Medicine, Emory University, Atlanta, GA, USA; 3Department of Dermatology, Emory University School of
Crimp C +3 more
doaj
BACKGROUND In the last two decades, it has become evident that secondary leukemias after Hodgkin's disease (HD) are mainly caused by the treatment with alkylating agents, especially mechlorethamine. Since 1978, the German-Austrian trials for childhood HD
M Riepenhausen +6 more
core +1 more source
Management of mycosis fungoides-type cutaneous T-cell lymphoma (MF-CTCL): focus on chlormethine gel
Daphné Denis,1 Nathalie Beneton,1 Kamel Laribi,2 Hervé Maillard1 1Dermatology Department, Centre Hospitalier Le Mans, Le Mans, France; 2Haematology Department, Centre Hospitalier Le Mans, Le Mans, France Abstract: Mycosis fungoides (MF) is ...
Denis D, Beneton N, Laribi K, Maillard H
doaj
ABSTRACT Purpose To describe age‐specific patterns of gonadotoxic alkylating‐agent exposure and evaluate how the cyclophosphamide equivalent dose (CED) framework captures real‐world exposure relevant to fertility preservation in females aged 0–43 years. Methods This descriptive study used a Japanese claims database.
Kentaro Taniguchi +7 more
wiley +1 more source
Posttransplant cutaneous T cell lymphomas are rare and have been reported to have a poor prognosis. We report the case of a follicular mycosis fungoides in a lung transplant recipient who was successfully treated with topical mechlorethamine, prior to ...
Venetz, J.P. +5 more
core +1 more source
Oncology drug repurposing as a blueprint for Alzheimer's therapy
Abstract Alzheimer's disease (AD) imposes substantial personal, social, and economic burdens, yet current therapies provide only modest slowing of clinical decline. Recent approvals of amyloid‐targeting antibodies confirm target engagement but also expose the limitations of single‐target strategies in a disease shaped by interacting processes ...
Viswanath Das, Marián Hajdúch
wiley +1 more source
JEADV Clinical Practice, Volume 5, Issue 3, Page 1010-1012, September 2026.
Farhanaz Panjshiri +2 more
wiley +1 more source
This study elucidates pesticide docking onto proteins encoded by differentially expressed genes, revealing interaction networks involving chemicals, genes, proteins, drugs and diseases. It highlights structural insights, regulatory pathways and potential therapeutic or environmental implications, providing a comprehensive understanding of the ...
Jyoti Kant Choudhari +4 more
wiley +1 more source

