Associations Between Physical Activity, Fitness, Perceived Health, Chronic Disease and Mortality in Adult Survivors of Childhood and Young Adult Hodgkin's Lymphoma: A Scoping Review. [PDF]
Cancers (Basel)Marmol-Perez A, Berkman AM, Ness KK.
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Identification of early events in nitrogen mustard pulmonary toxicity that are independent of infiltrating inflammatory cells using precision cut lung slices. [PDF]
Toxicol Appl PharmacolBellomo A +5 more
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Clonal Hematopoiesis and Therapy-Related Myeloid Neoplasms After Autologous Transplant for Hodgkin Lymphoma. [PDF]
J Clin OncolYan C +16 more
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Identification of novel genetic mutations for the treatment prognostication of canine lymphoma. [PDF]
NPJ Precis OncolTsang J +12 more
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Dysregulation of the mTOR pathway by mechlorethamine
Toxicology, 2023Mechlorethamine (HN2) is a derivative of the chemical warfare agent sulfur mustard (SM) and cutaneous exposure to HN2 is associated with dermal-epidermal junction (DEJ) disruption (vesication). The primary purpose of the present study was to investigate the effect of HN2 on the mammalian target of rapamycin (mTOR) signaling pathway using an in vivo ...
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Hypersensitivity to Mechlorethamine
Annals of Internal Medicine, 1981Excerpt To the editor: The recently published review by Weiss and Bruno (1) prompts us to report a second case of type 1 hypersensitivity to intravenous mechlorethamine.
KENNETH S. WILSON, SKARIA ALEXANDER
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Hyperbaric Oxygenation and Mechlorethamine Effectiveness
Archives of Surgery, 1963In order to test one of the possible radiomimetic qualities of alkylating agents, we have studied the influence of hyperbaric oxygen on the tumoricidal action of mechlorethamine (nitrogen mustard) in spontaneous mammary tumors of heterozygous, randomly bred Swiss-Webster mice.
R P, LEATHER, C, ECKERT
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Accidental intramuscular injection of mechlorethamine
Cancer, 1980A 55-year-old man with chronic, active diffuse psoriasis was accidentally given 30 mg of mechlorethmine deep into the buttock muscles. About 5 hours after the intramuscular (IM) mechlorethamine injection, 1/6 M sodium thiosulfate was infused around the intramuscular site.
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The use of chemotherapeutic agents as an adjunct to operative management of malignant disease is receiving considerable attention in current cancer research. Since the effects of these highly toxic drugs are not entirely limited to neoplastic tissue, however, knowledge of their effects on normal healing of wounds would be valuable.
C G, LONGENECKER, E T, KREMENTZ
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Topical mechlorethamine therapy for mycosis fungoides
British Journal of Dermatology, 1977Patients with limited skin involvement by mycosis fungoides were treated with daily topical mechlorethamine. Seven of thirteen patients had a complete remission of diseases. Six of these seven experienced a contact dermatitis and four underwent a successful topical desensitization programme.
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