Results 81 to 90 of about 5,025 (229)
Cancer Management and Research, 2018 Tingting Zhang,1 Yan Yao,2 Fubin Feng,3 Wenge Zhao,2 Jinhui Tian,4 Chao Zhou,3 Xue Wang,5 Shengjie Dong,6 Jia Li,2 Lingyu Qi,7 Changgang Sun3,8 1College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong
Zhang T +10 more
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Secondary 3‐Chloropiperidines: Powerful Alkylating Agents
ChemistryOpen, Volume 13, Issue 6, June 2024.The synthesis of secondary 3‐chloropiperidines and highly strained bicyclic aziridines is reported, including a new method for the selective mono‐chlorination of unsaturated primary amines. The novel compounds, which closely resemble natural alkylating agents, proved to be more active than previously reported 3‐chloropiperidines in a DNA cleavage assay,
Mats Georg +5 more
wiley +1 more source
THE INDUCTION OF GRAFT VERSUS HOST DISEASE IN MICE TREATED WITH CYCLOPHOSPHAMIDE [PDF]
, 1968 In these studies adult mice treated with cyclophosphamide and foreign immunologically competent cells developed a graft versus host disease which outwardly resembled that encountered in other experimental systems.
Owens, Albert H., Santos, George W.
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Interdisciplinary Toxicology, 2018 Mechlorethamine (HN2) is an alkylating agent and sulfur mustard gas mimetic which is also used in anticancer therapy. HN2 is associated with skin inflammation and blistering which can lead to secondary infections.
Benedette J. Cuffari +3 more
semanticscholar +1 more source
Fecal microbiota diversity in survivors of adolescent/young adult Hodgkin lymphoma: A study of twins [PDF]
, 2013 BACKGROUND: Adolescent/young adult Hodgkin lymphoma (AYAHL) survivors report fewer exposures to infections during childhood compared with controls, and they have functional lymphocyte aberrations.
Cozen, Wendy +9 more
core +2 more sources
Deciphering the interstrand crosslink DNA repair network expressed by Trypanosoma brucei [PDF]
, 2019 Interstrand crosslinks (ICLs) represent a highly toxic form of DNA damage that can block essential biological processes including DNA replication and transcription.
Dittani, A, WILKINSON, S
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Insights on cyclophosphamide metabolism and anticancer mechanism of action: A computational study
Journal of Computational Chemistry, Volume 45, Issue 10, Page 663-670, April 15, 2024.The outcomes of a density functional theory (DFT) computational mechanistic study of the main cyclophosphamide (CP) activation steps leading to the formation of the active phosphoramide mustard form and the DNA alkylating action of this latter are illustrated.
Eslam Dabbish +6 more
wiley +1 more source
CARBON DOTS: Bioimaging and Anticancer Drug Delivery
Chemistry – A European Journal, Volume 30, Issue 19, April 2, 2024.This review explores Carbon Dots (CDs) in cancer treatment, highlighting their synthesis, bioimaging applications, and role in drug delivery. The review details potential barriers to drug delivery, and details recent studies and developments, with a focus on the use of CDs as nanocarriers in drug delivery systems designed for the delivery of ...
Michał Bartkowski +4 more
wiley +1 more source
The Clinical Respiratory Journal, Volume 18, Issue 3, March 2024.This may be the first reported case with high PD‐L1 expression in primary pulmonary histiocytic sarcoma who may benefit from immunotherapy. Routine PD‐L1 expression detection is recommended for histiocytic sarcoma patients especially those who got advanced cancer.
Yuanjie Lin +3 more
wiley +1 more source
Adult life after surviving lymphoma in childhood [PDF]
, 2018 Introduction: Almost all pediatric lymphomas are malignant, high-grade tumors. The combined incidence of Hodgkin's disease (HD) and non-Hodgkin lymphoma (NHL) reaches 10 to 12 new cases a year per million children under the age of 16years, representing ...
von der Weid, Nicolas
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