Results 91 to 100 of about 4,334,118 (337)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Compliance with web content accessibility guidelines in ophthalmology social media posts
Scientific ReportsThis is a cross-sectional exploratory analysis of publicly available Internet data to examine compliance to web content accessibility guidelines (WCAG) on patient education social media posts in ophthalmology.
Meghan Sharma +5 more
doaj +1 more source
Mapping the Evolving Landscape of Audiovisual Translation and Media Accessibility
Anglica. An International Journal of English StudiesThis article explores the dynamic evolution of audiovisual translation (AVT) and media accessibility amid technological advances and shifting societal expectations.
Monika Zabrocka
doaj +1 more source
This paper provides a model of how media environments affect political polarization. We first develop a model of how media environments, characterized by their levels of accessibility and variety of content, interact with citizens' ideological views and ...
Campante, Filipe R., Hojman, Daniel
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The role of TIAS in shaping smart tourism: governance perspectives on choosing intelligent destinations [PDF]
Business AnalystPurposeThis research paper examines the transformative impact of technological integration on the governance of tourist destinations, focusing particularly on the smart destination governance paradigm.
R. Naveen Kumar +3 more
doaj +1 more source
Locking Out the Mother Corp: Nationalism and Popular Imaginings of Public Service Broadcasting in the Print News Media [PDF]
, 2007 Early promoters of public-service broadcasting (PSB) in Canada emphasized its democratic and nationalist merit. Of these twin pillars, only nationalism appears to still be standing.
Ferguson, Sue
core +3 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source