Results 61 to 70 of about 5,601,650 (302)

Termite: An Open-Source Grasshopper Plugin for Parametric Slicing in Architectural Clay 3D Printing

Journal of Manufacturing and Materials Processing
Over the last decade, 3D printing of clay has gained attention in architecture. Yet most slicing software is designed for thermoplastics with nozzle sizes between 0.3 and 1.0 mm.
Julian Jauk, Lukas Gosch, Hana Vašatko, Milena Stavric   +3 more
doaj   +1 more source

PARAMETRIC MODELLING (BIM) FOR THE DOCUMENTATION OF VERNACULAR CONSTRUCTION METHODS: A BIM MODEL FOR THE COMMISSARIAT BUILDING, OTTAWA, CANADA [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2013
Whether a house of worship or a simple farmhouse, the fabrication of a building reveals both the unspoken cultural aspirations of the builder and the inevitable exigencies of the construction process.
S. Fai, M. Filippi, S. Paliaga
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Comparing Native Crystal Structures and AlphaFold2 Predicted Water-Soluble G Protein-Coupled Receptor QTY Variants

Life, 2021
Accurate predictions of 3-dimensional protein structures by AlphaFold2 is a game-changer for biology, especially for structural biology. Here we present the studies of several native chemokine receptors including CCR5, CCR9, CXCR2 and CXCR4 determined by
Michael A. Skuhersky, Fei Tao, Rui Qing, Eva Smorodina, David Jin, Shuguang Zhang   +5 more
doaj   +1 more source

STopHC: A Harmful Content Detection and Mitigation Architecture for Social Media Platforms [PDF]

International Conference on Computational Photography
The mental health of social media users has started more and more to be put at risk by harmful, hateful, and offensive content. In this paper, we propose STOPHC, a harmful content detection and mitigation architecture for social media platforms.
Ciprian-Octavian Truică, A. Constantinescu, Elena-Simona Apostol   +2 more
semanticscholar   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Rough or Noisy? Metrics for Noise Estimation in SfM Reconstructions

Sensors, 2020
Structure from Motion (SfM) can produce highly detailed 3D reconstructions, but distinguishing real surface roughness from reconstruction noise and geometric inaccuracies has always been a difficult problem to solve.
Ivan Nikolov, Claus Madsen
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source