Results 101 to 110 of about 932,965 (310)
Are the media globalizing political discourse? The war on terrorism case study [PDF]
, 2004 The paper challenges the claim that an increasingly global media is creating a homogenisation of political discourses at the international level. In particular, it explores the extent to which the U.S. government managed to affect global perceptions of
Archetti, C
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
, 2004 Locative media uses portable, networked, location aware computing devices for user-led mapping and artistic interventions in which geographical space becomes its canvas.
Hemment, Drew
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Media bias and electoral discourse
La Revista Icono 14This study employs quantitative and artificial intelligence methods to scrutinize media coverage during an election campaign. Employing TF, TF*IDF, and word2vec for text quantification and vectorization, alongside UAMP and t-SNE for cluster analysis, we
Mar Castillo-Campos +2 more
doaj +1 more source
The Language USAge in the Discourse of Friday Preaching in Java, Indonesia [PDF]
, 2013 Tulisan ini hendak menjelaskan karakteristik khutbah Jum'at dalam perspektifsosio-pragmatik dan budaya Jawa. Data tulisan ini diambil secara purposifdari khutbah Jum'at di daearh Surakarta, Jawa Tengah.
Saddhono, K. (Kundharu)
core
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
The democratic rhetoric of the austerity measures [PDF]
, 2013 The main purpose of this paper is to make an analysis of the policy-legitimizing discourses of the political-economic executive in Portugal considering the social and economic crisis thecountry is going through, and how this democratic legitimation is ...
Van Vossole, Jonas
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source