Results 41 to 50 of about 3,082 (259)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Inside the Wardrobe: Fashioning a Fashionable Life

open access: yesEuropean Journal of Life Writing, 2019
This article looks to the manifestation of the personal wardrobe in digital fashion media. It focuses upon the example of British Vogue’s YouTube series ‘Inside the Wardrobe’ and episodes that feature, firstly Vogue Fashion Editor Sarah Harris and Vogue ...
Felice McDowell
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

KARTUN KARIKATUR MEDIA KOMUNIKASI SOSIAL DALAM MEDIA CETAK

open access: yesGelar: Jurnal Seni Budaya, 2016
Caricature Cartoon, a whole word that can be realized in the picture. Pictures like this are usually found in the print media, newspapers, magazines and books. Some of the readers sometimes only a cursory look, if by chance they are definitely worth high
Sri Indratmi Yudiarti
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Analisis Strategi Promosi Dalam Pengembangan Pariwisata Di Kabupaten Lebak Banten

open access: yesSains Manajemen, 2019
Kabupaten Lebak yang beribukota Rangkasbitung merupakan salah satu Kabupaten di Provinsi Banten yang menjadi kawasan pengembangan pariwisata karena memiliki banyak potensi pariwisata yang menarik.Diantaranya : Pantai Bagedur,Pantai Sawarna,Pantai Bayah ...
Yoga Adiyanto, Yuda Supriatna
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Learning global journalism: A course on journalism on developing countries in Africa and the Finnish freelance journalism market

open access: yesŽurnalistikos Tyrimai, 2009
A group of Finnish journalism students travelled to Zambia, Africa in November 2007. The field trip was a culmination for a course in journalism on developing  countries.
Jaana Hujanen
doaj   +1 more source

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