Results 51 to 60 of about 3,082 (259)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Venture Labor| Venture Labor and Media Work: The Canary Has Flown

open access: yesInternational Journal of Communication, 2017
The essays in this series provide valuable insights and commentaries on Neff’s Venture Labor. They show both the gains and losses and the winners and losers as work is transformed by the Internet and social media apps.
Paul M. Hirsch
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

ENGLISH-ISLAMOPHOBIA IN GERMANY: A CASE STUDY OF PEGIDA

open access: yesدی اسکالر, 2019
After the event of 9/11 in New York, Muslim countries have been affected badly with the ongoing war on terror. Muslim population which was affected due to this war, they started to move to other nation states.
Nauman Sial, Abid Zafar, Yasar Arafat
doaj  

Le fonds Jean Lattes : une archive photographique en construction

open access: yesIn Situ, 2018
The donation in 2011, by his widow Janine Lattes, of more than 180,000 photos taken by the photojournalist Jean Lattes (1917 - 1996) to the archive service of the Yvelines department forced its archivists to reflect on their practice.
Angelina Meslem   +2 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Venture Labor| Freelancing as the Good Life?

open access: yesInternational Journal of Communication, 2017
This article asks how venture labor manifests in the work of producing journalism on a freelance basis in a time of labor precarity. While freelancing offers journalists much-desired flexibility and autonomy, it is also a way for corporations to offload
Nicole S. Cohen
doaj  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

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