Results 51 to 60 of about 66,147 (308)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

KARTUN KARIKATUR MEDIA KOMUNIKASI SOSIAL DALAM MEDIA CETAK

open access: yesGelar: Jurnal Seni Budaya, 2016
Caricature Cartoon, a whole word that can be realized in the picture. Pictures like this are usually found in the print media, newspapers, magazines and books. Some of the readers sometimes only a cursory look, if by chance they are definitely worth high
Sri Indratmi Yudiarti
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Analisis Strategi Promosi Dalam Pengembangan Pariwisata Di Kabupaten Lebak Banten

open access: yesSains Manajemen, 2019
Kabupaten Lebak yang beribukota Rangkasbitung merupakan salah satu Kabupaten di Provinsi Banten yang menjadi kawasan pengembangan pariwisata karena memiliki banyak potensi pariwisata yang menarik.Diantaranya : Pantai Bagedur,Pantai Sawarna,Pantai Bayah ...
Yoga Adiyanto, Yuda Supriatna
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Learning global journalism: A course on journalism on developing countries in Africa and the Finnish freelance journalism market

open access: yesŽurnalistikos Tyrimai, 2009
A group of Finnish journalism students travelled to Zambia, Africa in November 2007. The field trip was a culmination for a course in journalism on developing  countries.
Jaana Hujanen
doaj   +1 more source

A sporting chance for women? Exploring gender imbalance on the sports desks of UK national newspapers [PDF]

open access: yes, 2016
Sports journalism has traditionally been seen as a male domain, and a number of researchers suggest that this tradition has not changed (Strong, 2007) . Sports reporters in the United Kingdom remain predominantly male, and despite increasingly more women
Franks, Suzanne, O'Neill, Deirdre
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Science and the media: securing the future [PDF]

open access: yes, 2010
A report by the Science and the Media Expert Group, in which actions and recommendations are made which are aimed at delivering changes to improve the quality of science in the media and also stimulate an important debate about the future of science ...

core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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