Results 71 to 80 of about 66,147 (308)
Higher education stimulating creative enterprise [PDF]
This report summarises the research undertaken by the Business & Community School at the University for the Creative Arts (UCA), analysing ways that higher ediucation (HEIs) can support, and indeed stimulate, the creative economy.
Campbell, Frances, Ely, Philip
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
The California Gig Economy Law
Photo by Morning Brew on Unsplash INTRODUCTION Employer-based insurance models work when the laws compelling employers to offer insurance are enforced. Corporate failure to provide insurance to full time employees undermines the system and results in
Anne Zimmerman
doaj +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
This podcast is a recording of Jim McGuigan's talk "The Work of Raymond Williams" that he presented in the CAMRI Research Seminar at the University of Westminster on October 15, 2014.
Jim McGuigan
doaj +1 more source
Freelance working: Mobile technology and social media
Freelance workers are important contributors to the United Kingdom’s (UK) economy and they are growing significantly not at least because technology enables them to work on their own account. Reports based on Labour Force Survey (LFS) data estimate that there were 1.9 million freelance workers in the UK in 2015, constituting 6% of all UK workers in ...
Reuschke, Darja, Wilkins, Annabelle H.
openaire +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
The 14-19 Diploma: partnering and piloting the agenda within Higher Education to enhance and inspire future learners [PDF]
The following description is taken from the pdf of the conference programme. In collaboration with local schools consortia, professional practitioners and widening participation partners, this paper reflects on successful pilot workshops already held ...
Laslett, Penny, Tappenden, Curtis
core
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source

