Results 151 to 160 of about 48,502,445 (376)
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
Twenty years at the margins: the Herman-Chomsky propaganda model, 1988-2008 [PDF]
2008 marks the 20th anniversary of the publication of Manufacturing Consent: The Political Economy of the Mass Media by Edward S. Herman and Noam Chomsky. This comment briefly assesses how the Herman-Chomsky Propaganda Model (PM) has been received within
Mullen, Andy
core
Neoliberalism Studies and Media Studies
AbstractThis short article provides an overview of the various theoretical and methodological approaches to analysing neoliberalism, paying particular attention to political-economic and governmental approaches (and the extent to which they can be contrasted or combined), and argues for a more theoretically- and methodologically-informed ...
openaire +2 more sources
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Embodied memory and curatorship in children’s digital video production [PDF]
Digital video production in schools is often theorised, researched and written about in two ways: either as a part of media studies practice or as a technological innovation, bringing new, “creative”, digital tools into the curriculum.
Potter, John
core +2 more sources
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Reactionary sensemaking: Mapping the micropolitics of online oppositional subcultures
Internet memes used to be funny, but somewhere in the mid-2010's, a darker dimension surfaced. This editorial explores this ‘reactionary turn’ in digital culture through a collection of articles and commentaries on ‘the micropolitics of online ...
Marc Tuters+4 more
doaj +1 more source
Delayed Reflections: Media and Journalism Data Deserts in the Post-Socialist Czech Republic
One of the key obstacles to the normative development of post-socialist media systems, in general, and the Czech Republic in particular, is the deferral of the thoughtful reflection and critical examination of the evolution of the media industry by ...
Lenka Waschková Císařová+2 more
doaj +1 more source
A Comparison of the Curves of Lipolytic Activity and Proteolysis of Certain Rapidly Growing Human Tubercle Bacilli in Media of Varied Composition. Studies in Acid-Fast Bacteria. IX [PDF]
A. I. Kendall, A. W. Walker, A. A. Day
openalex +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source