Results 61 to 70 of about 22,462 (202)

Cross‐material memory prediction: Influence of preoperative visual memory on postoperative verbal memory change after left anterior temporal lobe resection in people with epilepsy

Epilepsia, EarlyView.
Abstract Objective Left anterior temporal lobe resection (TLR) in people with epilepsy is associated with a high risk of postoperative verbal memory decline. Whereas substantial evidence supports the role of preoperative verbal memory in predicting postoperative verbal memory change, the potential contribution of preoperative visual memory has been ...
Lea Marie Reisch, Anne Hagemann, Johanna Lena Hopf, Florian J. Muecke, Friedrich G. Woermann, Christian G. Bien, Philip Grewe   +6 more
wiley   +1 more source

Epileptic arousals: A neglected clinical entity

Epilepsia, EarlyView.
Abstract Objective Epileptic arousals (EAs) are seizures characterized solely by arousal from sleep. EAs are unrecognized in current seizure classifications. Their subtle semiology and inconsistently detectable ictal activity in scalp electroencephalography (EEG) complicate differentiation from physiological arousals (PAs). This study characterizes EAs
Lea Fisel, Nóra Pető, Sotirios Kalousios, Nicolas Zabler, Armin Brandt, Peter C. Reinacher, Dieter Riemann, Mohammad F. Khazali, Andreas Schulze‐Bonhage   +8 more
wiley   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

Epilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Superficial layers of the medial entorhinal cortex replay independently of the hippocampus [PDF]

Science, 2017
Parallel computation in memory-making The hippocampus plays a central role in the encoding, consolidation, and recall of memories. Consolidation and recall are thought to be executed by the replay of previously acquired memory traces by hippocampal cell assemblies.
J. O’Neill, C.N. Boccara, F. Stella, P. Schoenenberger, J. Csicsvari   +4 more
openaire   +2 more sources

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Analysis of individualized brain–gut association networks and transcriptional patterns in major depressive disorder

Interdisciplinary Medicine, EarlyView.
Individualized brain–gut association networks suggest potential neuropathological mechanisms in MDD and MDDSI. Multilevel brain–gut association changes involving HSV‐1 and inflammation may be relevant to MDD, whereas alterations related to insulin metabolism may play a potential role in the neuropathological mechanisms of MDDSI.
Wei Wang, Baoyuan Zhu, Yuanyuan Huang, Liqin Liang, Zhaobo Li, Yunheng Diao, Minxin Guo, Heng Zhang, Jing Zhou, Fengchun Wu, Kai Wu   +10 more
wiley   +1 more source

Heterogenous Neuropathology in a Pedigree with RAB39B‐Related Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background In 2015, we reported a family with Parkinson's disease resulting from the RAB39B p.G192R (c.574G>A) variant. Since then, two affected brothers from the family have undergone autopsy. Objectives To characterize neuropathological findings, assess intracellular distribution of RAB39B protein, and examine the effect of p.G192R on α ...
Caitlin Latimer, Oswaldo Lorenzo‐Betancor, Dong‐Hui Chen, Kimmy Su, Marika Bogdani, Anna J. Park, Minsuh Kim, Joshua Weiss, Malia Callier, Ella H. Chiu, Sarah Fish, Jennifer L. Witt, Wendy H. Raskind, Marie Y. Davis, C. Dirk Keene, Cyrus P. Zabetian   +15 more
wiley   +1 more source

Astrocytes in the medial entorhinal cortex are required for spatial exploration

Cell Reports
Exploring the environment is essential for survival and has traditionally been attributed primarily to neuronal functions. However, the role of astrocytes in regulating exploratory behaviors remains poorly understood. Using fiber photometry and genetically encoded calcium indicators specifically targeted to astrocytes, we show that spatial exploration ...
Mingzhu, Huang, Zhiqi, Yang, Haoyu, Wang, Shaofan, Yang, Jin, Li, Shanshan, Liang, Teng, Teng, Chuanyan, Yang, Mingyue, Gong, Han, Qin, Xingyi, Li, Xiaowei, Chen, Xiang, Liao, Kuan, Zhang   +13 more
openaire   +2 more sources

Distinct Roles of Medial and Lateral Entorhinal Cortex in Spatial Cognition [PDF]

Cerebral Cortex, 2012
It is known that the entorhinal cortex plays a crucial role in spatial cognition in rodents. Neuroanatomical and electrophysiological data suggest that there is a functional distinction between 2 subregions within the entorhinal cortex, the medial entorhinal cortex (MEC), and the lateral entorhinal cortex (LEC).
van Cauter, Tiffany, Camon, Jeremy, Alvernhe, Alice, Elduayen, Coralie, Sargolini, Francesca, Save, Etienne   +5 more
openaire   +3 more sources

Predictive grid cells: Future spatial representations in the hippocampal-entorhinal circuit

Neuroscience Research
Place cells in the hippocampus and grid cells in the entorhinal cortex have long been interpreted as neural representations of an animal’s current location in space. However, an increasing amount of theoretical and experimental evidence suggests that the
Ayako Ouchi
doaj   +1 more source