Results 81 to 90 of about 24,307 (213)

Paroxysmal slow waves mark ictal networks

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy diagnosis and treatment monitoring are hindered by the episodic, heterogeneous expression of seizures and by normal‐appearing scalp electroencephalography (EEG) in many patients. We previously described paroxysmal slow‐wave events (PSWEs), brief epochs of broadband slowing detectable on EEG in people with epilepsy.
Florent J. M. Boyer‐Aymé   +13 more
wiley   +1 more source

Anatomical and functional investigation of the deep medial entorhinal cortex [PDF]

open access: yes, 2019
Spatial computations are thought to be processed in the hippocampal-entorhinal network and involve neurons with spatially selective firing properties.
Gerlei, Klára Zsófia
core  

Medial Entorhinal Cortex Selectively Supports Temporal Coding by Hippocampal Neurons [PDF]

open access: yes, 2017
Recent studies have shown that hippocampal “time cells” code for sequential moments in temporally organized experiences. However, it is currently unknown whether these temporal firing patterns critically rely on upstream cortical input. Here we employ an
Smeglin, VA   +13 more
core   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

open access: yesEpilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

The role of the perirhinal cortex in visual learning in the rat [PDF]

open access: yes, 1999
The aim of this thesis was to investigate the role of the perirhinal cortex in visual discrimination learning in the rat. Experiment one measured postoperative reacquisition of two sets of concurrent visual discriminations acquired at different time ...
Machin, Penelope Elizabeth
core  

Status epilepticus: Updates on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Heterogenous Neuropathology in a Pedigree with RAB39B‐Related Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background In 2015, we reported a family with Parkinson's disease resulting from the RAB39B p.G192R (c.574G>A) variant. Since then, two affected brothers from the family have undergone autopsy. Objectives To characterize neuropathological findings, assess intracellular distribution of RAB39B protein, and examine the effect of p.G192R on α ...
Caitlin Latimer   +15 more
wiley   +1 more source

Superficial layers of the medial entorhinal cortex replay independently of the hippocampus [PDF]

open access: yesScience, 2017
Parallel computation in memory-making The hippocampus plays a central role in the encoding, consolidation, and recall of memories. Consolidation and recall are thought to be executed by the replay of previously acquired memory traces by hippocampal cell assemblies.
J. O’Neill   +4 more
openaire   +2 more sources

Involvement of human amygdala and orbitofrontal cortex in hunger-enhanced memory for food stimuli [PDF]

open access: yes, 2001
We used positron emission tomography to measure regional cerebral blood flow (rCBF) in 10 healthy volunteers performing a recognition memory task with food and non-food items.
Morris, J.   +3 more
core  

The circuitry and function of layer 1 interneurons in the medial entorhinal cortex [PDF]

open access: yes
For mammals to navigate through a complex environment and remember paths to previous destinations, neural processing must occur in the hippocampal formation.
Armstrong, Jack
core   +1 more source

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