Results 1 to 10 of about 27,537 (233)

The median effective analgesic concentration of ropivacaine in ultrasound-guided interscalene brachial plexus block after arthroscopic rotator cuff repair [PDF]

open access: yesFrontiers in Pharmacology, 2022
Background: The median effective analgesic concentration (MEAC) of ropivacaine in interscalene brachial plexus block (ISBPB) for postoperative analgesia after arthroscopic rotator cuff repair (ARCR) has not been determined. Therefore, this study aimed to
Cheng Xu   +5 more
doaj   +6 more sources

The Median Effective Analgesic Concentration of Ropivacaine in Sciatic Nerve Block Guided by Ultrasound After Arthroscopic Anterior Cruciate Ligament Reconstruction: A Double-Blind Up-Down Concentration-Finding Study [PDF]

open access: yesFrontiers in Medicine, 2022
BackgroundThe median effective analgesic concentration (MEAC; EC50 = effective concentration in 50% patients) of ropivacaine in sciatic nerve block guided by ultrasound (US) required for effective postoperative analgesia following arthroscopic anterior ...
Cheng Xu   +6 more
doaj   +6 more sources

Median Effective Analgesic Concentration of Ropivacaine in Ultrasound-Guided Interscalene Brachial Plexus Block as a Postoperative Analgesia for Proximal Humerus Fracture: A Prospective Double-Blind Up-Down Concentration-Finding Study [PDF]

open access: yesFrontiers in Medicine, 2022
BackgroundThe innervation of the proximal humerus fracture is complicated and unclear. The use of interscalene nerve block has been effective as postoperative analgesia for patients, but the optimal concentration of usage is unknown.MethodThis study was ...
Yang Liu   +6 more
doaj   +6 more sources

Comparative antinociceptive effect of aspirin and aspirin nano particles in semisolid formulae in mice [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2021
Aspirin are commonly used analgesic, anti-inflammatory, and anti-pyretic drug in medicine, oral route is the most common one for drug administration as a result it will produce different adverse effects like peptic ulcer, nephropathy, and ...
Labeeb H. Al- Alsadoon   +2 more
doaj   +1 more source

Effects of hydrogen peroxide-induced oxidative stress on the plasma concentration and pharmacokinetics of ketorolac in chicks [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2023
The aim was to determine the impact of oxidative stress (OS), induced by hydrogen peroxide (H2O2), on the ketorolac plasma concentration and pharmacokinetics in the chicks.
Rafal L. Abdulah, Yaareb J. Mousa
doaj   +1 more source

Pharmacodynamics and pharmacokinetics interaction between nefopam and tramadol in the broiler chicks model [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2022
No former studies are dealing with the pharmacological (pharmacodynamics and pharmacokinetics) interaction between nefopam and tramadol in the chicks' model.
Yaareb J. Mousa, Mahmood B. Mahmood
doaj   +1 more source

The pharmacokinetics of phenylbutazone and its interaction with dexamethasone in chicks [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2023
The present study aims to investigate the influence of dexamethasone administration on the pharmacokinetics of phenylbutazone and its plasma concentration as well as its pharmacological interaction in a chick model.
Sahar K. Abdulhamid, Yaareb J. Mousa
doaj   +1 more source

The Effect of Adding Ondansetron and Metoclopramide to Intravenous Acetaminophen on Pain Control and Post-operative Nausea and Vomiting: A Randomized Double-blind Clinical Trial [PDF]

open access: yesJournal of Evidence-Based Care, 2023
IntroductionAlthough laparoscopic surgery causes less postoperative pain than open surgery, however, the pain at the site of the laparoscopic port incision and in the shoulder and upper abdomen are the main complaints.
Mohsen Saber Moghaddamranjbar   +2 more
doaj   +1 more source

Pharmacokinetic profile of injectable tramadol in the koala (Phascolarctos cinereus) and prediction of its analgesic efficacy.

open access: yesPLoS ONE, 2021
Tramadol is used as an analgesic in humans and some animal species. When tramadol is administered to most species it undergoes metabolism to its main metabolites M1 or O-desmethyltramadol, and M2 or N-desmethyltramadol, and many other metabolites.
Benjamin Kimble   +3 more
doaj   +1 more source

Antinociceptive and Antipruritic Effects of HSK21542, a Peripherally-Restricted Kappa Opioid Receptor Agonist, in Animal Models of Pain and Itch

open access: yesFrontiers in Pharmacology, 2021
Kappa opioid receptor (KOR) agonists have been promising therapeutic candidates, owing to their potential for relieving pain and treating intractable pruritus.
Xin Wang   +12 more
doaj   +1 more source

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