Results 151 to 160 of about 452,355 (274)

Determination of the Median Effective Dose of Dexmedetomidine for the Prevention of Emergence Agitation in Geriatric Patients Undergoing Major Open Surgery With General Anesthesia: A Prospective, Double-Blinded, Dose-Response Trial. [PDF]

Dose Response, 2021
Wang W, Zhou H, Sun A, Xiao J, Dong J, Xu H.   +5 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

The median effective dose of ropivacaine for ultrasound-guided peripheral nerve block around the hip capsule in elderly patients with intertrochanteric fractures. [PDF]

BMC Anesthesiol
Jin S, Wang C, Wu Q, Ke P, Lin C, Ren P, Zou Z, Yu Y, Lin L.   +8 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Obesity Reduces the Median Effective Dose of Remimazolam in Aged 6–18 Pediatric Patients for Procedural Sedation

Drug Design, Development and Therapy
Tian-Tian Liu,1 Junyan Chen,1 Xiao Jin,1 Zhong-Sai Yang,1 Xu-Qi Yu,1 Fei Xiao,1 Xiao-Dong Huang2 1Department of Anesthesiology, the Affiliated Women and Children’s Hospital of Ningbo University, Ningbo City, Zhejiang Province, People’s Republic of China;
Liu TT, Chen J, Jin X, Yang ZS, Yu XQ, Xiao F, Huang XD   +6 more
doaj  

The Impact of Sex on the Median Effective Dose of Dexmedetomidine for Preoperative Sedation in Adults Undergoing Upper Limb Surgery: An Up-and-Down Sequential Allocation Study. [PDF]

Drug Des Devel Ther
Fan G, Han M, Wang S, Zhang M, Kang F, Li J.   +5 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Exploring the median effective dose of ciprofol for anesthesia induction in patients with heart valve disease: a prospective, single-arm, single-centre study. [PDF]

BMC Anesthesiol
Mao Q, Liang B, Lu Y, Luo D, He F, Zhou L, Liu G, Chen Y, Xie Y.   +8 more
europepmc   +1 more source

An Analysis of the Wilson-Worcester Method for Determining the Median Effective Dose of Pertussis Vaccine [PDF]

American Journal of Public Health and the Nations Health, 1948
M, PITTMAN, J E, LIEBERMAN
openaire   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source