Results 181 to 190 of about 8,368,619 (264)

The median effective dose of ropivacaine for ultrasound-guided peripheral nerve block around the hip capsule in elderly patients with intertrochanteric fractures. [PDF]

BMC Anesthesiol
Jin S, Wang C, Wu Q, Ke P, Lin C, Ren P, Zou Z, Yu Y, Lin L.   +8 more
europepmc   +1 more source

Determination of the Median Effective Dose of Dexmedetomidine for the Prevention of Emergence Agitation in Geriatric Patients Undergoing Major Open Surgery With General Anesthesia: A Prospective, Double-Blinded, Dose-Response Trial. [PDF]

Dose Response, 2021
Wang W, Zhou H, Sun A, Xiao J, Dong J, Xu H.   +5 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Obesity Reduces the Median Effective Dose of Remimazolam in Aged 6–18 Pediatric Patients for Procedural Sedation

Drug Design, Development and Therapy
Tian-Tian Liu,1 Junyan Chen,1 Xiao Jin,1 Zhong-Sai Yang,1 Xu-Qi Yu,1 Fei Xiao,1 Xiao-Dong Huang2 1Department of Anesthesiology, the Affiliated Women and Children’s Hospital of Ningbo University, Ningbo City, Zhejiang Province, People’s Republic of China;
Liu TT, Chen J, Jin X, Yang ZS, Yu XQ, Xiao F, Huang XD   +6 more
doaj  

Median effective dose (ED50) of ciprofol combined with alfentanil for suppressing cervical dilation responses during hysteroscopy: a prospective Dixon up-and-down study. [PDF]

BMC Anesthesiol
Zhang C, Zhu Y, Zeng L, Zhu J, Chen J, Zhang T, Tao Y, Li S, Zhong M, Hua F, Liang W.   +10 more
europepmc   +1 more source

Median effective dose (ED₅₀) of paracetamol and morphine for postoperative pain: a study of interaction.

British Journal of Anaesthesia, 2014
A. Zeidan, J. X. Mazoit, M. A. Abdullah, H. Maaliki, Th Ghattas, A. Saifan   +5 more
semanticscholar   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

The Impact of Sex on the Median Effective Dose of Dexmedetomidine for Preoperative Sedation in Adults Undergoing Upper Limb Surgery: An Up-and-Down Sequential Allocation Study. [PDF]

Drug Des Devel Ther
Fan G, Han M, Wang S, Zhang M, Kang F, Li J.   +5 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Exploring the median effective dose of ciprofol for anesthesia induction in patients with heart valve disease: a prospective, single-arm, single-centre study. [PDF]

BMC Anesthesiol
Mao Q, Liang B, Lu Y, Luo D, He F, Zhou L, Liu G, Chen Y, Xie Y.   +8 more
europepmc   +1 more source