Results 61 to 70 of about 22,390,894 (295)
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
A mediation effect refers to the effect transmitted by a mediator intervening in the relationship between an exposure variable and a response variable.
Wentao Cao, Joseph Hagan, Qingzhao Yu
doaj +1 more source
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
Mediation analysis with principal stratification [PDF]
Abstract In assessing the mechanism of treatment efficacy in randomized clinical trials, investigators often perform mediation analyses by analyzing if the significant intent‐to‐treat treatment effect on outcome occurs through or around a third intermediate or mediating variable: indirect and direct effects, respectively.
Gallop, Robert +5 more
openaire +4 more sources
Mediation is a procedure in which an intermediary without decision-making powers (the mediator) systematically facilitates communication between the parties of a conflict with the aim of enabling the parties
International Finance Corporation
core +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Mediation analysis issues and recommendations [PDF]
This editorial outlines and responds to some of the most frequently asked questions regarding mediation analysis. Specifically, six key issues are addressed with reference to the state-of-the-art mediation literature.
Jun, Hwa Cheah +4 more
core +1 more source
Analysis of Chaperone-Mediated Autophagy [PDF]
Chaperone-mediated autophagy (CMA) is a selective type of autophagy whereby a specific subset of intracellular proteins is targeted to the lysosome for degradation. These proteins are identified by a chaperone that targets them to lysosomes. There, they are translocated into the organelle lumen through a lysosomal membrane receptor/translocation ...
Y R, Juste, A M, Cuervo
openaire +2 more sources
Mediation, arbitration and negotiation [PDF]
We compare three common dispute resolution processes { negotiation, mediation, and arbitration { in the framework of Crawford and Sobel (1982). Under negotiation, the two parties engage in (possibly arbitrarily long) face-to-face cheap talk.
Horner, J. +3 more
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