Results 191 to 200 of about 711,203 (301)

The relationship between cognitive function and quality of life in older hypertension patients: a parallel mediation effect of frailty and medication discrepancies. [PDF]

BMC Geriatr
Zhou L, Chen Z, Li X, Wu Y, Guan H, Yin W, Sun K, Yu Q.   +7 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Daily sitting time and hyperuricemia in US adults: A dose-response association with the mediation effect of renal function-related indicators (NHANES 2007-2018). [PDF]

Medicine (Baltimore)
Li L, Wang F, Guo Q.
europepmc   +1 more source

SUMOylation mediates brassinosteroid effects [PDF]

Nature Reviews Molecular Cell Biology, 2014
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Understanding autistic identity contingencies: The chain mediation effect of autism acceptance and loneliness in ableist microaggressions and social camouflage. [PDF]

Autism
Guan S, Takahashi F, Wada M, Takashina HN, Ueda M, Kawashima M, Kawaguchi Y, Kato T, Ogawa S, Tsuchiya K, Oshima F.   +10 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Depressive Symptoms and Glycemic Control Among Children and Adolescents With Diabetes: The Mediation Effect of Self-Care Behaviors. [PDF]

Pediatr Diabetes
Song H, Huang Y, Li J, Ding Y, Luo Z, Chen M, Cao X.   +6 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Association between outdoor physical activity and positive mental health in adolescence: estimating the mediation effect of autonomy, competence and relatedness. [PDF]

Int J Behav Nutr Phys Act
Drapeau C, Lenze L, Montiel C, Gallant F, Bélanger M, Doré I.   +5 more
europepmc   +1 more source