Results 71 to 80 of about 227,127 (342)

Brief Report: Medical Assistance in Dying in Patients With Lung Cancer

open access: yesJTO Clinical and Research Reports, 2022
Introduction: Medical assistance in dying (MAiD) was legalized in Canada in 2016. Cancer accounts for 60% to 65% of MAiD cases. Lung cancer, the most common cause of cancer death, is expected to makeup a large number of MAiD cases.
Sara Moore, MD   +2 more
doaj   +1 more source

Kidney transplant outcomes after medical assistance in dying

open access: yesCanadian Urological Association Journal, 2021
Introduction: After nearly four years of Canadian experience with medical assistance in dying (MAiD), the clinical volume of organ transplantation following MAiD remains low. This is the first Canadian report evaluating recipient outcomes from kidney transplantation following MAiD.
Patrick P, Luke   +7 more
openaire   +3 more sources

How the mass media report social statistics: A case study concerning research on end-of-life decisions [PDF]

open access: yes, 2010
This is the post-print version of the final paper published in Social Science & Medicine. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural ...
Bauman   +44 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

L’assistance à mourir : un tour d’horizon comparatif des définitions juridiques

open access: yesSociologies, 2023
Euthanasia, assisted suicide, medical assistance in dying, death with dignity: these and many other different terms are used around the world to capture various types of assistance in dying.
Jocelyn Downie   +3 more
doaj  

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Assisted Dying in Canada: Ideology Masquerading as Medicine?

open access: yesCanadian Journal of Bioethics
The Canadian medical assistance in dying (MAID) law is commonly understood as a type of medically-based euthanasia and/or assisted suicide (EAS) law. I argue it is instead an autonomy-only EAS regime masquerading as such.
Scott Y. H. Kim
doaj   +1 more source

Physicians who object to medical assistance in dying [PDF]

open access: yesCanadian Medical Association Journal, 2018
This letter is in response to a recent CMAJ news article.[1][1] It bears emphasizing that freedom of conscience is not the freedom to do what one wants but to do what one must. It is a natural right which is enshrined in the Canadian Charter of Rights and Freedoms, but would exist as a right ...
W Joseph, Askin, Thomas, Bouchard
openaire   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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