Results 101 to 110 of about 11,426,298 (383)

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Your evidence? Machine learning algorithms for medical diagnosis and prediction

Human Brain Mapping, 2019
Computer systems for medical diagnosis based on machine learning are not mere science fiction. Despite undisputed potential benefits, such systems may also raise problems.
B. Heinrichs, S. Eickhoff
semanticscholar   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Explainable AI in medical imaging: an interpretable and collaborative federated learning model for brain tumor classification

Frontiers in Oncology
IntroductionA brain tumor is a collection of abnormal cells in the brain that can become life-threatening due to its ability to spread. Therefore, a prompt and meticulous classification of the brain tumor is an essential element in healthcare care ...
Qurat-ul-ain Mastoi, Shahid Latif, Sarfraz Brohi, Jawad Ahmad, Abdulmajeed Alqhatani, Mohammed S. Alshehri, Alanoud Al Mazroa, Rahmat Ullah   +7 more
doaj   +1 more source

ON THE IMPORTANCE OF PHRENOLOGY IN MEDICAL DIAGNOSIS. [PDF]

The Lancet
n ...
openaire   +2 more sources

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Autism Data Classification Using AI Algorithms with Rules: Focused Review

Bioengineering
Autism Spectrum Disorder (ASD) presents challenges in early screening due to its varied nature and sophisticated early signs. From a machine-learning (ML) perspective, the primary challenges include the need for large, diverse datasets, managing the ...
Abdulhamid Alsbakhi, Fadi Thabtah, Joan Lu   +2 more
doaj   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

SympCoughNet: symptom assisted audio-based COVID-19 detection

Frontiers in Digital Health
COVID-19 remains a significant global public health challenge. While nucleic acid tests, antigen tests, and CT imaging provide high accuracy, they face inefficiencies and limited accessibility, making rapid and convenient testing difficult.
Yuhao Lin, Xiu Weng, Bolun Zheng, Weiwei Zhang, Zhanjun Bu, Yu Zhou   +5 more
doaj   +1 more source

Short view of leukemia diagnosis and treatment in Iran [PDF]

, 2015
Background: Early diagnosis and treatment of leukemia patients remains a fundamental aim in clinical oncology, especially in developing country. Present study highlights the basic requirements of these patients in Iran.
Alizadeh, S., Azad, M., Biniaz, R.B., Fard, A.D., Goudarzi, M., Kaviani, S., Mobarra, N., Moghadasi, M.H., Nasiri, H., Sahmani, M., Sarookhani, M.R., Vatanmakan, M.   +11 more
core   +1 more source