Magnetic-Particle-Sensing Based Diagnostic Protocols and Applications
Magnetic particle-labeled biomaterial detection has attracted much attention in recent years for a number of reasons; easy manipulation by external magnetic fields, easy functionalization of the surface, and large surface-to-volume ratio, to name but a ...
Tsukasa Takamura+5 more
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The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
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Application of Open-Source, Low-Code Machine-Learning Library in Python to Diagnose Parkinson's Disease Using Voice Signal Features [PDF]
Parkinson's disease (PD), the second most prevalent neurodegenerative disorder after Alzheimer's disease, affects approximately 10 million individuals worldwide.
Daniel Hilário da Silva+3 more
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Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
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THE DIFFERENTIAL DIAGNOSIS OF SYPHILIS AND PARASYPHILIS OF THE NERVOUS SYSTEM: Introduction to a Discussion on Syphilis and Parasyphilis of the Nervous System at the Medical Society of London on November 13th, 1911 [PDF]
F. W. Mott
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
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Recent Advances in Medical Diagnosis and Treatment [PDF]
A. H. Douthwaite
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This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
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Study on the performance of X-ray machines used in K-fluorescent devices
Since Roentgen discovered X-rays, X-rays have been widely used in medical diagnosis and industrial non-destructive testing. With the improvement of the performance of aviation technology and instrumentation, higher requirements have been set for the ...
Mengshi Li+3 more
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NEW VIEWS ON THE PATHOLOGY, DIAGNOSIS, AND TREATMENT OF GASTRIC AND DUODENAL ULCER: A British Medical Association Lecture Delivered before the Tunbridge Wells Division on January 20th, 1920 [PDF]
A. F. Hurst
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