Results 161 to 170 of about 9,201,948 (316)
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Rear view of Medical College Hospital, September 1953
, 1953 This glass lantern slide features a ground view of the rear side of the Medical College of South Carolina Hospital during its construction in September ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
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Unhealthy Digital Marketing Among Aboriginal People in Australia: Findings From the #DigitalMob Pilot Study. [PDF]
Health Promot J AustrBrowne J +17 more
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Medical College of South Carolina Hospital
This glass lantern slide features a rear view of the Medical College of South Carolina ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
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New Roper, Medical College Hospital construction, October 1953
, 1953 This glass lantern slide features a ground view of a color photograph of construction of the New Roper Hospital and the Medical College Hospital construction in October ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
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Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Southwest view of Medical College quadrangle
This glass lantern slide features a ground view of the southwest side of the Medical College of South Carolina ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
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