Results 141 to 150 of about 8,826,721 (317)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
RADIATION HYGIENE: INTERACTION OF SCIENCE AND PRACTICE
Радиационная гигиена, 2017 A short sketch of history of radiation hygiene formation as a scientific discipline is presented, its conventional directions are outlined, and the perspectives of development are pointed out.
S. I. Ivanov +3 more
doaj
Medical Center grounds diagram
This glass lantern slide features a black and white diagram of the Medical College of South Carolina Medical Center ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core
Medical College Hospital, 1953
, 1953 This glass lantern slide features an aerial view of a color photograph of construction of the Medical College of South Carolina Hospital in mid ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
MEDICAL EXPOSURE AND STRATEGY OF ITS PROPHYLAXIS
Радиационная гигиена, 2017 The characteristic of a modern medical exposure of the population is submitted. The features of the using of ionizing irradiation sources in medicine, including patients' exposure doses, are presented.
T. V. Ponomareva +2 more
doaj
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Issues of Medical Exposure and Occupational Exposure in Medical
Japanese Journal of Health Physics, 2019 openaire +2 more sources
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source