Results 81 to 90 of about 10,185,878 (314)

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Minutes: Medical School Faculty Assembly, May 11, 2006

, 2006
University of Minnesota. Medical School Faculty Assembly. (2006). Minutes: Medical School Faculty Assembly, May 11, 2006.
University of Minnesota. Medical School Faculty Assembly
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Minutes: Medical School Faculty Assembly, May 8, 2003

, 2003
University of Minnesota. Medical School Faculty Assembly. (2003). Minutes: Medical School Faculty Assembly, May 8, 2003.
University of Minnesota. Medical School Faculty Assembly
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Faculty Members’ Promotion: Challenges and Solutions [PDF]

Strides in Development of Medical Education, 2021
Sara Shafian, Mahla Salajegheh
doaj   +1 more source

Use of a CME workshop to introduce and promote the specialty of Family Medicine in Ethiopia

African Journal of Primary Health Care & Family Medicine, 2010
Use of a CME workshop to introduce and promote the specialty of Family Medicine in ...
Jane Philpott, Miliard Derbew
doaj   +1 more source

Minutes: Medical School Faculty Assembly, June 13, 2002

, 2002
University of Minnesota. Medical School Faculty Assembly. (2002). Minutes: Medical School Faculty Assembly, June 13, 2002.
University of Minnesota. Medical School Faculty Assembly
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Open Access an der Universitätsbibliothek Duisburg-Essen: Schwerpunkt Medizin

GMS Medizin – Bibliothek – Information, 2019
The article first provides a brief overview of the overall university development of open access at the University of Duisburg-Essen (UDE). It then traces the increasing proportion of open access publications at the UDE, with a focus on the golden open ...
Wibker, Katrin, Falkenstein-Feldhoff, Katrin   +1 more
doaj   +1 more source