Results 71 to 80 of about 74,228 (295)

Assessment of Hearing Health Among Adults in Rural Health Clinics

The Laryngoscope, EarlyView.
Rural health clinics are a critical healthcare system tasked with improving health in rural communities. This study recruited 403 adults from 10 rural healthcare clinics throughout rural Kentucky, mostly within Appalachia, to screen for hearing loss and evaluate the utilization of diagnostic hearing healthcare and found that 70% of participants ...
Mit A. Patel, David Adkins, Laura Bellnier, Anthony Mahairas, Matthew L. Bush   +4 more
wiley   +1 more source

Futility in TAVI: A scoping review of definitions, predictive criteria, and medical predictive models.

PLoS ONE
BackgroundTranscatheter Aortic Valve Implantation (TAVI) procedures are rapidly expanding, necessitating a more extensive stratification of patients with aortic stenosis.
Charlie Ferry, Jade Fiery-Fraillon, Mario Togni, Stephane Cook   +3 more
doaj   +1 more source

The ethics of blood stewardship and quantitative futility assessments to predict certain death in neurotrauma patients

Frontiers in Medicine
Universally accepted guidelines to predict futile resuscitation in severely bleeding trauma patients with traumatic brain injury do not exist. These patients may consume vast volumes of blood products in futile cases, which is especially problematic ...
Marie N. Karam, Jenny Chen, Samuel J. Thomas, Miguel Velasco, Afsheen Mansoori, Molly L. Feller, Mark D. Fox, Ernest E. Moore, Ernest E. Moore, Hunter B. Moore, Peter K. Moore, Vraj S. Patel, Jeffery M. Bao, Connor P. Schmitt, Joseph G. Robuck, Aleksey T. Zielinski, Scott G. Thomas, Daniel F. Lewandowski, Connor M. Bunch, Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group   +19 more
doaj   +1 more source

Outcomes of Cardiopulmonary Resuscitation and Estimation of Healthcare Costs in Potential ‘Do Not Resuscitate’ Cases

Sultan Qaboos University Medical Journal, 2016
Objectives: Cardiopulmonary resuscitation (CPR) is a life-saving procedure which may fail if applied unselectively. ‘Do not resuscitate’ (DNR) policies can help avoid futile life-saving attempts among terminally-ill patients.
Akhwand S. Ahmad, Sayed Mudasser, Muhammad N. Khan, Hafiz N. H. Abdoun   +3 more
doaj   +1 more source

Following on the Foreign Corrupt Practices Act: The Dynamic Shareholder Derivative Suit [PDF]

, 2013
Corporations that have allegedly violated the Foreign Corrupt Practices Act (FCPA) increasingly face a new threat of liability: cases brought by private plaintiffs in follow-on derivative suits.
Jara, Gabriela
core   +1 more source

Phase I dose-escalation trial of the oral AKT inhibitor uprosertib in combination with the oral MEK1/MEK2 inhibitor trametinib in patients with solid tumors. [PDF]

, 2020
PurposeThis study aimed to determine the safety, tolerability, and recommended phase II doses of trametinib plus uprosertib (GSK2141795) in patients with solid tumors likely to be sensitive to MEK and/or AKT inhibition.MethodsThis was a phase I, open ...
Becerra, Carlos, D'Amelio, Anthony M, Ellis, Catherine, Gauvin, Jennifer, Gonzalez, Rene, Heist, Rebecca S, Ibrahim, Nageatte, Kalyana-Sundaram, Shanker, Kleha, Joseph F, Kurzrock, Razelle, Leonowens, Cathrine, Means-Powell, Julie, Tan, Antoinette R, Tolcher, Anthony W, Valero, Vincente, Wang, Chenxi, Werner, Theresa L, Yan, Li   +17 more
core  

An Open‐Label Phase 1b Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of ANX005 in Patients with Huntington's Disease

Movement Disorders, EarlyView.
Complement activation is implicated in Huntington's disease; ANX005 is a potent inhibitor of component C1q. ANX005 exhibited a generally manageable safety profile with rapid reduction in C1q in the cerebrospinal fluid. Functional ability on composite Unified Huntington's Disease Rating Scale and total functional capacity was maintained, with potential ...
Rajeev Kumar, Pinky Agarwal, Karen Anderson, Daniel Claassen, Marissa Dean, Andrew Duker, Burton Scott, Benjamin Hoehn, Ann Mongan, Ping Lin, Ellen Cahir‐McFarland, Lori Taylor, Glenn Morrison, Ted Yednock, Sanjay Keswani, Henk‐Andre Kroon   +15 more
wiley   +1 more source

Perceived potentially inappropriate treatment in the PICU: frequency, contributing factors and the distress it triggers

Frontiers in Pediatrics
BackgroundPotentially inappropriate treatment in critically ill adults is associated with healthcare provider distress and burnout. Knowledge regarding perceived potentially inappropriate treatment amongst pediatric healthcare providers is limited ...
Amrita Sarpal, Amrita Sarpal, Michael R. Miller, Michael R. Miller, Claudio M. Martin, Claudio M. Martin, Robert W. Sibbald, Robert W. Sibbald, Kathy N. Speechley, Kathy N. Speechley, Kathy N. Speechley   +10 more
doaj   +1 more source

Morte e Morrer em Tempos de COVID-19

Clinical and Biomedical Research, 2021
A pandemia da COVID-19 está tendo impactos em toda a sociedade humana. Muitas questões antes abordadas no plano individual pela Bioética agora tem o desafio de ter o seu enfoque ampliado para toda a sociedade.
José Roberto Goldim, Marcia Santana Fernandes   +1 more
doaj  

'Often there is a good deal to be done, but socially rather than medically': the psychiatric social worker as social therapist, 1945-70 [PDF]

, 2011
Seeking to align psychiatric practice with general medicine following the inauguration of the National Health Service, psychiatric hospitals in post-war Britain deployed new treatments designed to induce somatic change, such as ECT, leucotomy and ...
Long, Vicky
core   +1 more source