Results 111 to 120 of about 2,823,528 (278)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Understanding the key differences between ISO 15189:2022 and ISO 15189:2012 for an improved medical laboratory quality of service

Romanian Journal of Laboratory Medicine, 2023
Ilinca Radu, Chiriac Ionuț A., Luțescu Dan A., Ganea Ionela, Hristodorescu-Grigore Smaranda, Dănciulescu-Miulescu Rucsandra-Elena   +5 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Cybersecurity requirement of ISO 15189 - a simplified protocol for laboratories

Romanian Journal of Laboratory Medicine, 2023
Ilinca Radu, Luțescu Dan Adrian, Chiriac Ionuț Adrian, Hristodorescu-Grigore Smaranda, Stănescu-Spînu Iulia-Ioana, Ganea Ionela, Gherlan Iuliana, Dănciulescu-Miulescu Rucsandra-Elena   +7 more
doaj   +1 more source

Assessing medical biochemistry professionals’ knowledge, attitudes, and behaviors regarding green and sustainable medical laboratory practices in Türkiye

Türk Biyokimya Dergisi
This study aims to evaluate the knowledge, attitudes, and behaviors of medical biochemistry professionals in Türkiye regarding green and sustainable medical laboratory (GSML) practices.
Yurt Emine Feyza, Alpdemir Medine, Şeneş Mehmet   +2 more
doaj   +1 more source

Medical laboratory practice in Malawi - Current status. [PDF]

Afr J Lab Med, 2023
Nayupe SF, Mbulaje P, Munharo S, Patel P, Lucero-Prisno DE.   +4 more
europepmc   +1 more source

Determination of reference ranges using medical laboratory date [PDF]

, 1994
H Rahi, Ali Reza Kiyani
openalex  

Analytical Quality in the Medical Laboratory - The ASAP Concept. Part 2: Internal Quality Control [PDF]

, 2012
Hedwig Stepman, Dietmar Stöckl
openalex   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source