Results 161 to 170 of about 4,158,488 (347)

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

What would the medical students like to know in laboratory medicine?

open access: yesJournal of Health Science and Medical Research (JHSMR), 2003
Laboratory medicine is an important subject in medical education. According to the principles of student-based teaching, an evaluation of the students' perception towards the taught subjects is important.
V Wiwanitkit
doaj  

Assessing medical biochemistry professionals’ knowledge, attitudes, and behaviors regarding green and sustainable medical laboratory practices in Türkiye

open access: yesTürk Biyokimya Dergisi
This study aims to evaluate the knowledge, attitudes, and behaviors of medical biochemistry professionals in Türkiye regarding green and sustainable medical laboratory (GSML) practices.
Yurt Emine Feyza   +2 more
doaj   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

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