Results 31 to 40 of about 929,810 (294)

Epidemiology of antibiotic resistance in culture-positive hospitalized patients in selected hospitals in Khartoum, Sudan [PDF]

, 2019
Objective: To study the prevelence of antibiotic resistance and the prevalent bacterial isolates in hospitalized patients in Khartoum hospitals. Materials & Methods: A cross-sectional prevalence study was carried out during the period of April ...
Abdalrahman, Ihab B, Al-Hassan, Leena, El Amin, Nagwa M, Osman, Einas A   +3 more
core   +4 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Multi-omics and machine learning-based profiling of severity signatures in Mycoplasma pneumoniae infection in children

iScience
Summary: Mycoplasma pneumoniae pneumonia (MPP) is a common respiratory infection in children; however, the mechanisms driving its progression to severe disease remain poorly understood.
Guiqiu Li, Ying Wei, Wenzheng Wang, Zhili Hu, Qiaowen Yang, Lili He, Yun Gao, Xiulan Lai   +7 more
doaj   +1 more source

The Impact of Experiential Learning in Host-Pathogen Research on Medical Students’ Interests and Attitudes towards Microbiology and Immunology

Journal of Microbiology & Biology Education, 2021
There is a shortage of residents in the infectious diseases (IDs) specialty due to a lack of interest in this field. If the choice of an ID subspecialty is linked to medical school experiences, then how we teach microbiology and immunology could be a ...
Jorge Cervantes, Bo-Young Hong
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Screening for heterogeneous drug resistance in tuberculosis and its impact on clinical prognosis: A comprehensive review

iScience
Summary: Tuberculosis (TB) remains a leading global health threat, with the rise of drug-resistant (DR-TB) strains posing a significant impediment to disease control.
Xiaoyun Du, Keqing Shi, Hao Zhang, Yingzhi Chong   +3 more
doaj   +1 more source

Biogeotechnology, Biocorrosion, and Remediation—Three Areas of Modern Applied Environmental Microbiology

Microorganisms, 2022
For many years, medical microbiology and food microbiology have been the most studied areas of microbial biology [...]
Mikhail Vainshtein, Tatiana Abashina
doaj   +1 more source

Tests on medical microbiology [PDF]

, 2013
МИКРОБИОЛОГИЯ ...
Generalov, I. I., Zheleznyak, N. V.
core  

The role of microbiology and pharmacy departments in the stewardship of antibiotic prescribing in European hospitals [PDF]

, 2007
This observational, cross-sectional study describes the role played by clinical microbiology and pharmacy departments in the stewardship of antibiotic prescribing in European hospitals.
Bruce, Julie, Cookson, Barry, Gould, I.M., Krcmery, Vladimir, MacKenzie, Fiona, Mollison, Jill, Monnet, Dominique L., van der Meer, Jos W.M.   +7 more
core   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source