Results 61 to 70 of about 62,376 (291)

Falling short: examination of the validity of methods used to identify paediatric hospital falls in NSW, Australia

Public Health Research & Practice, 2020
Objective: Hospital falls are a major cause of costly harm. This descriptive epidemiological study reports the results of a data linkage and medical record review to examine the relative utility of these methods for identifying paediatric in-hospital ...
Daniela Feuerlicht , Maria Agaliotis , Reece Hinchcliff   +2 more
doaj   +1 more source

The Family Nurse Partnership to reduce maltreatment and improve child health and development in young children: the BB:2–6 routine data-linkage follow-up to earlier RCT

Public Health Research, 2021
Background: The short-term effectiveness (to 24 months post partum) of a preventative home-visiting intervention, the Family Nurse Partnership, was previously assessed in the Building Blocks trial (BB:0–2).
Michael Robling, Fiona Lugg-Widger, Rebecca Cannings-John, Julia Sanders, Lianna Angel, Sue Channon, Deborah Fitzsimmons, Kerenza Hood, Joyce Kenkre, Gwenllian Moody, Eleri Owen-Jones, Rhys Pockett, Jeremy Segrott, Thomas Slater   +13 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Creating a Powerful Platform to Explore Health in a Correctional Population: A Record Linkage Study.

PLoS ONE, 2016
We used record linkage to create a data repository of health information of persons who were federally incarcerated in Ontario and Canada. We obtained records from 56,867 adults who were federally incarcerated between January 1, 1998 and December 31 ...
Kathryn E McIsaac, Shanna Farrell MacDonald, Nelson Chong, Andrea Moser, Rahim Moineddin, Angela Colantonio, Avery Nathens, Flora I Matheson   +7 more
doaj   +1 more source

First-generation migrants’ use of psychotropic medication in Northern Ireland: a record linkage study [PDF]

International Journal of Mental Health Systems, 2019
Abstract Purpose There is a recent and growing migrant population in Northern Ireland. However, rigorous research is absent regarding access to mental health care by different migrant groups. In order to address this knowledge gap, this study aimed to identify the relative use of psychotropic medication between the ...
Tania Bosqui, Dermot O’Reilly, Ari Väänänen, Kishan Patel, Michael Donnelly, David Wright, Ciara Close, Anne Kouvonen   +7 more
openaire   +6 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Report on the use of linked data relating to Aboriginal and Torres Strait Islander people [PDF]

, 2013
The Council of Australian Governments funded the Australian Institute of Health and Welfare and the Australian Bureau of Statistics to review past, ongoing and planned data linkage studies that have an Indigenous focus.

core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Effect of inpatient and outpatient care on treatment outcome in tuberculosis: a cohort study

Revista Panamericana de Salud Pública, 2018
Objective. To identify individual- and health services–related factors associated with deaths in subjects diagnosed with tuberculosis (TB). Methods. A nonconcurrent cohort study with passive follow-up was conducted using a probabilistic linkage method to
Marli S. Rocha, Gisele P. Oliveira, Valéria Saraceni, Fernanda P. Aguiar, Claudia M. Coeli, Rejane S. Pinheiro   +5 more
doaj   +1 more source