Results 61 to 70 of about 8,285,529 (212)

Application of Social Constructivism in Medical Education [PDF]

open access: yes, 2020
The purpose of this study is to discuss the main principles and concepts of social constructivism, examine the literature on the application of social constructivism in medical education, and explore the meaning and limitations of the utilization of ...
Korean Medical Education Review (의학교육논단)
core   +1 more source

Impact of Comorbidities on Survival in Gastric, Colorectal, and Lung Cancer Patients

open access: yesJournal of Epidemiology, 2019
Background: The presence of comorbidities in cancer patients may influence treatment decisions and prognoses. This study aimed to examine the impact of comorbidities on overall survival in Japanese patients diagnosed with major solid tumors.
Toshitaka Morishima   +9 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Record-linkage methodology for prescribing research

open access: yes, 2001
Record-linkage refers to the linking together of data relating to the same individual from separate source files. In this paper, we discuss ways in which the technique can enhance observational prescribing research in large populations.
Libby, G.   +5 more
core   +1 more source

Secure Privacy Preserving Record Linkage of Large Databases by Modified Bloom Filter Encodings

open access: yesInternational Journal of Population Data Science, 2017
Objective In most European settings, record linkage across different institutions has to be based on personal identifiers such as names, birthday or place of birth. To protect the privacy of research subjects, the identifiers have to be encrypted.
Rainer Schnell, Christian Borgs
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Record-Linkage from a Technical Point of View [PDF]

open access: yes
TRecord linkage is used for preparing sampling frames, deduplication of lists and combining information on the same object from two different databases.
Rainer Schnell
core  

Manifesto for medical research [PDF]

open access: yes, 2015
The MRCG want to ensure there is a dynamic medical research environment in Ireland. Ensuring priority investment for medical research will help to deliver patient care, public health service transformation and economic and enterprise development.
Medical Research Charities Group
core  

Record Linkage in Healthcare

open access: yes, 2010
Recent years have witnessed the development of new record linkage technologies that are increasingly being used for data integration in various application settings.
Kaveepan Lertwachara   +2 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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