Results 81 to 90 of about 62,376 (291)
Record-Linkage from a Technical Point of View [PDF]
TRecord linkage is used for preparing sampling frames, deduplication of lists and combining information on the same object from two different databases.
Rainer Schnell
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Probabilistic record linkage and an automated procedure to minimize the undecided-matched pair problem [PDF]
Probabilistic record linkage allows the assembling of information from different data sources. In this article, we present a procedure in case a one-to-one relationship between records in different files is expected but is not found only by applying the ...
Kenneth Hill, Carla Jorge Machado
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Privacy Preserving Probabilistic Record Linkage (P3RL): a novel method for linking existing health-related data and maintaining participant confidentiality. [PDF]
, 2015 BACKGROUND Record linkage of existing individual health care data is an efficient way to answer important epidemiological research questions. Reuse of individual health-related data faces several problems: Either a unique personal identifier, like ...
Schmidlin, Kurt +2 more
core +1 more source
GMS Medizinische Informatik, Biometrie und Epidemiologie, 2006 The Society for Paediatric Oncology and Haematology (GPOH) and the corresponding Competence Network Paediatric Oncology and Haematology conduct various clinical trials. The comprehensive analysis requires reliable identification of the recruited patients.
Pommerening, Klaus +2 more
doaj
Probabilistic data linkage: a case study of comparative effectiveness in COPD
Drugs in Context, 2013 Background: In this era of comparative effectiveness research, new, advanced techniques are being investigated by the research community to overcome the limitations of existing data sources.
Christopher M Blanchette +3 more
doaj +1 more source
International Journal of Population Data Science, 2020 Introduction: Individual, social and economic circumstances faced by young mothers can challenge a successful start in life for their children. Intervening early might enhance life chances for both mother and child.
Fiona V Lugg-Widger +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Cancer Medicine, 2020 Cancer treatments for older patients must account for heterogeneity in health and functional status. Guidelines advocate the use of geriatric assessments (GAs), but comprehensive assessments are laborious and the utility of specific GA domains remains ...
Toshitaka Morishima +3 more
doaj +1 more source