Results 81 to 90 of about 214,875 (289)

A novel locus for autosomal recessive primary microcephaly (MCPH6) maps to 13q12.2 [PDF]

, 2003
Key points: • Autosomal recessive primary microcephaly (MCPH) is a genetic disorder in which an affected subject is born with a head circumference >3 SD below the expected mean and is mentally retarded.
Costa, S.M.R., Hampshire, D.J., Leal, G.F., Roberts, E., Silva, E.O., Woods, C.G.   +5 more
core   +2 more sources

Secure Privacy Preserving Record Linkage of Large Databases by Modified Bloom Filter Encodings

International Journal of Population Data Science, 2017
Objective In most European settings, record linkage across different institutions has to be based on personal identifiers such as names, birthday or place of birth. To protect the privacy of research subjects, the identifiers have to be encrypted.
Rainer Schnell, Christian Borgs
doaj   +1 more source

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

Building Data-Driven Pathways From Routinely Collected Hospital Data:A Case Study on Prostate Cancer [PDF]

, 2015
Background: Routinely collected data in hospitals is complex, typically heterogeneous, and scattered across multiple Hospital Information Systems (HIS).
Adriansyah, A, Cios, KJ, Holmström, Benny, Lang, M, Luc, Kd, Mans, R, Mans, R, Pearson, SD, Safran, C   +8 more
core   +2 more sources

A process to deduplicate individuals for regional chronic disease prevalence estimates using a distributed data network of electronic health records

Learning Health Systems, 2022
Introduction Learning health systems can help estimate chronic disease prevalence through distributed data networks (DDNs). Concerns remain about bias introduced to DDN prevalence estimates when individuals seeking care across systems are counted ...
Kenneth A. Scott, Sara Deakyne Davies, Rachel Zucker, Toan Ong, Emily McCormick Kraus, Michael G Kahn, Jessica Bondy, Matt F. Daley, Kate Horle, Emily Bacon, Lisa Schilling, Tessa Crume, Romana Hasnain‐Wynia, Seth Foldy, Gregory Budney, Arthur J. Davidson   +15 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Effect of inpatient and outpatient care on treatment outcome in tuberculosis: a cohort study

Revista Panamericana de Salud Pública, 2018
Objective. To identify individual- and health services–related factors associated with deaths in subjects diagnosed with tuberculosis (TB). Methods. A nonconcurrent cohort study with passive follow-up was conducted using a probabilistic linkage method to
Marli S. Rocha, Gisele P. Oliveira, Valéria Saraceni, Fernanda P. Aguiar, Claudia M. Coeli, Rejane S. Pinheiro   +5 more
doaj   +1 more source

Statistical supervised meta-ensemble algorithm for medical record linkage

Journal of Biomedical Informatics, 2019
Identifying unique patients across multiple care facilities or services is a major challenge in providing continuous care and undertaking health research. Identifying and linking patients without compromising privacy and security is an emerging issue in the big data era.
Kha Vo, Jitendra Jonnagaddala, Siaw-Teng Liaw   +2 more
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Impact of Comorbidities on Survival in Gastric, Colorectal, and Lung Cancer Patients

Journal of Epidemiology, 2019
Background: The presence of comorbidities in cancer patients may influence treatment decisions and prognoses. This study aimed to examine the impact of comorbidities on overall survival in Japanese patients diagnosed with major solid tumors.
Toshitaka Morishima, Yoshifumi Matsumoto, Nobuyuki Koeda, Hiroko Shimada, Tsutomu Maruhama, Daisaku Matsuki, Kayo Nakata, Yuri Ito, Takahiro Tabuchi, Isao Miyashiro   +9 more
doaj   +1 more source