Results 61 to 70 of about 185,354 (288)

Using CamiTK for rapid prototyping of interactive Computer Assisted Medical Intervention applications [PDF]

, 2013
Computer Assisted Medical Intervention (CAMI hereafter) is a complex multi-disciplinary field. CAMI research requires the collaboration of experts in several fields as diverse as medicine, computer science, mathematics, instrumentation, signal processing,
Bailet, Mathieu, Cinquin, Philippe, Deram, Aurelien, Fiard, Gaelle, Fouard, Celine, Hungr, Nikolai, Luboz, Vincent, Payan, Yohan, Promayon, Emmanuel, Sarrazin, Johan, Saubat, Nicolas, Selmi, Sonia Yuki, Troccaz, Jocelyne, Voros, Sandrine   +13 more
core   +4 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Preliminary Validation of Nitinol Rod Driven Discrete Continuum Robot for Transoral Surgery by Planar Path Planning with CT Images

Robotics
A Nitinol rod-driven discrete continuum robot with two sections and eight units was developed to support clinicians in performing transoral surgery. The robot measures 120 mm in length, with each unit having a diameter of 15 mm and a height of 20 mm. The
Yeoun-Jae Kim, Ji Eun Oh, Daehan Wi
doaj   +1 more source

Endoscopic laser resection of a ureteral tumour in primary multiple malignant neoplasms

Вестник урологии, 2021
A case of the ureteral tumour endoscopic treatment is presented in a patient with primary multiple malignancies. In the case of polyneoplasia, there are usually two or more neoplasms of different localizations, including the organs of the urinary system.
B. G. Guliev, B. K. Komyakov, Zh. P. Avazkhanov   +2 more
doaj   +1 more source

Magnetic-Visual Sensor Fusion-based Dense 3D Reconstruction and Localization for Endoscopic Capsule Robots [PDF]

, 2018
Reliable and real-time 3D reconstruction and localization functionality is a crucial prerequisite for the navigation of actively controlled capsule endoscopic robots as an emerging, minimally invasive diagnostic and therapeutic technology for use in the ...
Almalioglu, Yasin, Araujo, Helder, Ornek, Evin Pinar, Sitti, Metin, Turan, Mehmet, Yanik, Mehmet Fatih   +5 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

A Non-Rigid Map Fusion-Based RGB-Depth SLAM Method for Endoscopic Capsule Robots

, 2017
In the gastrointestinal (GI) tract endoscopy field, ingestible wireless capsule endoscopy is considered as a minimally invasive novel diagnostic technology to inspect the entire GI tract and to diagnose various diseases and pathologies.
Almalioglu, Yasin, Araujo, Helder, Konukoglu, Ender, Sitti, Metin, Turan, Mehmet   +4 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Medical Robotics

, 2012
Medical robotics is an interdisciplinary field that focuses on developing electromechanical devices for clinical applications. The goal of this field is to enable new medical techniques by providing new capabilities to the physician or by providing assistance during surgical procedures.
Ahmad Taher Azar, M. Sam Eljamel
openaire   +2 more sources