Results 101 to 110 of about 8,462,363 (413)

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Differences in fear of failure and college adjustment by type of medical school entrance extrinsic motivation using a latent profile analysis [PDF]

Korean Journal of Medical Education
Purpose The decision to enroll in medical school is largely influenced by extrinsic motivation factors. It is necessary to explore the factors that affect pre-med students’ motivation to enter medical school and their college adjustment, and to develop ...
So Jung Yune, Ie Byung Park, Hyo Hyun Yoo, Kwi Hwa Park   +3 more
doaj   +1 more source

THE CAMBRIDGE MEDICAL SCHOOL. [PDF]

The Lancet, 1902
n ...
openaire   +2 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Explain the Concept of “Islamic Medicine

Health, Spirituality and Medical Ethics, 2022
Background and Objectives: Today, various medical schools have emerged, including modern, complementary and traditional medicine, Chinese and recently Islamic medicine, each of which has played a role in the process of human health based on its own ...
Mehdi Zarvandi
doaj  

Bedside ultrasound education in Canadian medical schools: A national survey

Canadian Medical Education Journal, 2016
Background This study was carried out to determine the extent and characteristics of bedside ultrasound teaching in medical schools across Canada. Methods A cross-sectional, survey-based study was used to assess undergraduate bedside ultrasound education
Peter Steinmetz, O. Dobrescu, Sharon Oleskevich, John Lewis   +3 more
semanticscholar   +1 more source

THE CHEMISTRY OF THE MEDICAL SCHOOL. [PDF]

JAMA: The Journal of the American Medical Association, 1904
In the present condition of rapid growth and devel opment in our medical schools, one of the vexing problems which has come up for solution is with reference to the kind and amount of chemistry which should be taught. It is evident to any one who takes the trouble to look that the methods and concepts of somewhat advanced chemistry are becoming more ...
openaire   +3 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Changing medical student attitudes to patient safety: A multicentre study [PDF]

, 2018
Background: Although patient safety is becoming widely taught in medical schools, its effect has been less rigorously evaluated. We describe a multicentre study to evaluate student changes in patient safety attitudes using a standardized instrument, the ...
Hu, Wendy, Nagle, Amanda, Oates, Kim, Walker, Ben, Wiley, Janice, Wilson, Ian   +5 more
core   +3 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source