Results 101 to 110 of about 1,460,105 (366)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Stress among medical students of Gorgan (South East of Caspian Sea), Iran [PDF]

open access: yes, 2008
Objective: This study aims to estimate the prevalence of psychological stress and association between the levels of stress and study variables among Gorgan medical students.
Alizadeh, F.   +4 more
core  

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

open access: yesFEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh   +7 more
wiley   +1 more source

Wie häufig und belastend sind negative Erfahrungen im Medizinstudium? – Ergebnisse einer Online-Befragung von Medizinstudierenden [Frequency and perceived severity of negative experiences during medical education in Germany – Results of an online-survery of medical students]

open access: yesGMS Zeitschrift für Medizinische Ausbildung, 2012
[english] Aims: Negative experiences during the course of medical education have been reported in many countries, but little is known about the perceived severity of these experiences.
Gágyor, Ildikó   +8 more
doaj   +1 more source

Physical activity education in the undergraduate curricula of all UK medical schools: are tomorrow's doctors equipped to follow clinical guidelines? [PDF]

open access: yes, 2012
Physical activity (PA) is a cornerstone of disease prevention and treatment. There is, however, a considerable disparity between public health policy, clinical guidelines and the delivery of physical activity promotion within the National Health Service ...
Chew, S   +4 more
core   +2 more sources

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

How Much Does it Cost to Train a Physician in Colombia?

open access: yesRevista Ciencias de la Salud, 2018
Introduction: The objective is to estimate the costs to society of training a doctor at either a public or a private university in Colombia. Materials and methods: Direct and indirect costs were estimated in 2016 Colombian pesos (average exchange rate 3 ...
Yaneth Gil-Rojas   +6 more
doaj   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

open access: yesFEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado   +4 more
wiley   +1 more source

Factors affecting the concentrations of heavy metals in precipitation of Tehran using factor analysis method

open access: yesسلامت و محیط, 2016
Backgrounds and Objectives: Quantity of trace metals in the wet precipitation can illustrate the environmental pollution of different urban areas. Up to now, there is no study regarding the chemistry of wet precipitation in Tehran .The objectives of this
H Kamani   +4 more
doaj  

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