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A 3 Week Geriatric Education Program for 4th Year Medical Students at Dalhousie University [PDF]
, 2003 Purpose -Population demographics are shifting towards an increased average age. Yet, many medical schools still do not have mandatory comprehensive education in Geriatric Medicine.
Freter , M.D., FRCPC, Susan +2 more
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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
It's About Time: Learning Time and Educational Opportunity in California High Schools [PDF]
, 2014 A new study by the UCLA Institute for Democracy, Education and Access (IDEA) found that teachers in high-poverty schools are more likely than their peers in low-poverty schools to report more time lost for academic instruction due to poor access to ...
John Rogers, Nicole Mirra
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Career options in Medicine [PDF]
, 2004 Students accepted for admission to the MD course at the University of Malta are understandably elated and initially may not appreciate the long-term implications of their choice.
Vassallo, Josanne
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Some aspects of medical care in the USSR [PDF]
, 1967 As a participant in the World Health Organization Seminar on Medical Care, which was held earlier this year in the Soviet Union, I had the opportunity of observing certain characteristic features of the Soviet system of medical care which, in some ...
Abela-Hyzler, P.
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source