Results 51 to 60 of about 1,460,105 (366)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

An outline of the genesis and transformation of medical schools in the Kielce region, 1945–2014

open access: yesStudia Medyczne, 2019
The research presents the history of the establishment and transformation of medical schools over the years 1945–2014 in the Kielce region. After the Second World War, a lamentable situation transpired in the region regarding the numbers of adequately ...
Ewa Zaczek-Kucharska   +2 more
doaj   +1 more source

Teaching statistics to medical students using problem-based learning: the Australian experience [PDF]

open access: yes, 2004
Background: Problem-based learning (PBL) is gaining popularity as a teaching method in UK medical schools, but statistics and research methods are not being included in this teaching.
A Howe   +3 more
core   +3 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Differences in fear of failure and college adjustment by type of medical school entrance extrinsic motivation using a latent profile analysis [PDF]

open access: yesKorean Journal of Medical Education
Purpose The decision to enroll in medical school is largely influenced by extrinsic motivation factors. It is necessary to explore the factors that affect pre-med students’ motivation to enter medical school and their college adjustment, and to develop ...
So Jung Yune   +3 more
doaj   +1 more source

Business schools inside the academy: What are the prospects for interdepartmental research collaboration? [PDF]

open access: yes, 2014
Established literature about the role of business schools tends towards more parochial concerns, such as their need for a more pluralist and socially reflexive mode of knowledge production (Starkey and Tiratsoo 2007; Starkey et al 2009) or the failure of
Currie, Graeme   +3 more
core   +1 more source

There are no schools for medical editors

open access: yesSouth African Medical Journal, 2013
There are no schools for medical editors. So warned Dan Ncayiayana, editor emeritus of the SAMJ. He is correct. Editorship is learned on the job. I have been fortunate to be the mentee of the retiring, but not-yet-retired, managing editor, J P van Niekerk, as I proudly assume the role of editor of this journal.
openaire   +4 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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