Results 101 to 110 of about 1,943,319 (338)

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Realizing the value of complex medical technology: Demonstrating cost-effectiveness is not enough. [PDF]

open access: yesClin Transl Radiat Oncol, 2023
Hehakaya C   +4 more
europepmc   +1 more source

O trabalho médico: questões acerca da autonomia profissional

open access: yesCadernos de Saúde Pública
O autor analisa algumas questões da prática médica relacionadas com a autonomia técnica que caracteriza a ação profissional. Nesse sentido aponta a existência simultânea do lado científico e do lado empírico-pragmático da medicina, mais conhecido como a ...
Lilia B. Schraiber
doaj  

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

Navigating the Paradox: Challenges and Strategies of University Students Managing Mental Health Medication in Real-World Practices [PDF]

open access: yesarXiv
Mental health has become a growing concern among university students. While medication is a common treatment, understanding how university students manage their medication for mental health symptoms in real-world practice has not been fully explored.
arxiv  

Chinese Medical Device Market and The Investment Vector [PDF]

open access: yesarXiv, 2016
China has attracted increasing amounts of foreign investment since it opened its doors to the world and whilst many analysts have focused on foreign investment in popular areas, little has been written about medical device investment. The purpose of this article is to analyze the status of the Chinese medical device market from the perspective of the ...
arxiv  

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

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