Results 121 to 130 of about 2,307,247 (311)

Does management matter in scientific laboratories? : evidence from Harvard Medical School

open access: yes, 2018
Thesis: S.M. in Technology and Policy, Massachusetts Institute of Technology, School of Engineering, Institute for Data, Systems, and Society, Technology and Policy Program, 2018.Thesis: S.M., Massachusetts Institute of Technology, Department of ...
Hillen, Florian, S.M. Massachusetts Institute of Technology
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

"Tamed Diseases": The Medical Rationalization of Addiction

open access: yesYixue yu zhexue
Academic discussions often focus on issues such as doctor-patient relationship and social control in the medical process, interpreting the development path of medicalization from the perspective of social construction. In the field of addiction research,
Zhengxiao WANG
doaj   +1 more source

The Diffusion of Medical Technology: Free Enterprise and Regulatory Models in the U.S.A

open access: yes, 1991
The diffusion of technology in the US has taken place in an environment of both regulation and free enterprise. Each has been subject to manipulation by doctors and medical administrators that has fostered unprecedented ethical dilemmas and legal ...
Warner, Susan E.   +5 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Caring for children with new medical technology at home: parental perspectives. [PDF]

open access: yesBMJ Paediatr Open, 2023
Pitch N   +8 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Introduction : Technology and Medical Practice: Blood, Guts and Machines

open access: yes, 2010
"Modern medicine is highly technological, with advanced technologies being used in diagnosis and care to provide knowledge about the patient, define bodily states and structure everyday medical interventions and divisions of labour. Whilst supporting and
Berner, Boel,, Johnson, Ericka,
core  

The market of medical office buildings [PDF]

open access: yes, 2012
Thesis (S.M. in Real Estate Development)--Massachusetts Institute of Technology, Program in Real Estate Development in Conjunction with the Center for Real Estate, 2012.Cataloged from department-submitted PDF version of thesis.
Wei, Yu-Hua, S.M. Massachusetts Institute of Technology
core  

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