Results 141 to 150 of about 1,943,319 (338)

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

SoK: Security and Privacy Risks of Medical AI [PDF]

open access: yesarXiv
The integration of technology and healthcare has ushered in a new era where software systems, powered by artificial intelligence and machine learning, have become essential components of medical products and services. While these advancements hold great promise for enhancing patient care and healthcare delivery efficiency, they also expose sensitive ...
arxiv  

On Medical Technology In Ancient Mesopotamia

open access: yes, 2010
Proceedings of the International Conference "Oeil malade et mauvais oeil", Collège de France, Paris, 23rd June ...
openaire   +3 more sources

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

open access: yesMolecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric   +11 more
wiley   +1 more source

Combining development, capacity building and responsible innovation in GCRF-funded medical technology research. [PDF]

open access: yesDev World Bioeth, 2022
Bezuidenhout L   +5 more
europepmc   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Novas tecnologias reprodutivas: doação de óvulos. O que pode ser novo nesse campo?

open access: yesCadernos de Saúde Pública
Este artigo discute as "novas" tecnologias reprodutivas. Através da interrogação dessa adjetivação, são analisadas estratégias e contradições que mantêm como novo esse conjunto de técnicas e experiências médicas iniciadas há mais de duas décadas e que ...
Marilena V. Corrêa
doaj  

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