Results 61 to 70 of about 4,104,345 (353)
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
A Review of the State of the Art for the Internet of Medical Things
SciThe technological developments in the Internet of Things (IoT), data science, artificial intelligence, wearable sensors, remote monitoring, decision support systems, fog, and edge systems have transformed digital healthcare. Especially after the pandemic,
Peter Matthew +8 more
doaj +1 more source
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Integrating digital and narrative medicine in modern healthcare: a systematic review
Medical Education OnlineThe increasing integration of digital technologies in healthcare, such as electronic health records, telemedicine, and diagnostic algorithms, improved efficiency but raised concerns about the depersonalization of care. Narrative medicine has emerged as a
Efthymia Efthymiou
doaj +1 more source
Using digital watermarking to enhance security in wireless medical image transmission [PDF]
, 2010 This is the published version of the article. Copyright 2010 Mary Ann Liebert Inc.During the last few years, wireless networks have been increasingly used both inside hospitals and in patients’ homes to transmit medical information.
Aggeliki Giakoumaki +10 more
core +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Digital Twins of Biological Systems: A Narrative Review
IEEE Open Journal of Engineering in Medicine and BiologyThe concept of Digital Twins (DTs), software models that mimic the behavior and interactions of physical or conceptual objects within their environments, has gained traction in recent years, particularly in medicine and healthcare research.
Ghufran A. Alsalloum +3 more
doaj +1 more source
Steady-state energy balance in animal models of obesity and weight loss [PDF]
, 2016 Supported by European Union Seventh Framework Programme (FP7/2007-2013, n°266408 (Full4Health)), the Joint Programme of the Medical Faculty of Norwegian University of Science and Technology (NTNU) and St. Olav’s University Hospital, the Liaison Committee
Barrett, Perry +7 more
core +2 more sources
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
, 2021 The medical field is creating large amount of data that physicians are unable to decipher and use efficiently. Moreover, rule-based expert systems are inefficient in solving complicated medical tasks or for creating insights using big data. Deep learning
Bizopoulos, Paschalis +1 more
core +1 more source