Results 91 to 100 of about 1,351,031 (350)
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Haoqi Liu,1,2 Ziqiang Yao,1,2 Shuangjiao Shi,1 Feng Zheng,1– 3 Xia Li,1,4 Zhuqing Zhong1,2 1Nursing Department, The Third Xiangya Hospital, Central South University, Changsha, People’s Republic of China; 2Xiangya Nursing School, Central South University,
Liu H +5 more
doaj
Background With the accessibility and widespread use of mobile phones, mobile phone apps targeting medication adherence may be useful tools to help patients take medications as prescribed.
J. Y. Park +4 more
semanticscholar +1 more source
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar +3 more
wiley +1 more source
An overview of medication adherence: Measurement methods and interventions [PDF]
Medication adherence is essential for achieving therapeutic outcomes. However, many patients do not follow their prescribed medication regimens. About 50% of patients do not adhere to their pharmacotherapy, making medication adherence a widespread issue.
Miceva Dijana +6 more
doaj +1 more source
A Systematic Review of Medication Adherence Thresholds Dependent of Clinical Outcomes
Background: In pharmacotherapy, the achievement of a target clinical outcome requires a certain level of medication intake or adherence. Based on Haynes's early empirical definition of sufficient adherence to antihypertensive medications as taking ≥80 ...
Pascal C Baumgartner +3 more
semanticscholar +1 more source
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Medication adherence can be defined as the extent to which one’s medication‐taking behaviour follows that mutually agreed upon by the prescribing physician. Optimal medication adherence is often deemed crucial for the success of a patient's treatment, as
A. Milosavljevic +2 more
semanticscholar +1 more source
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source

