Results 71 to 80 of about 2,458,624 (375)
Advanced Science, EarlyView.Novel carbon‐11 labeled pyrimidine derivatives are developed as PET imaging probes for visualizing sigma‐1 receptors in the brain. [11C]CNY‐01 demonstrates superior brain uptake and binding specificity in both rodents and non‐human primates. The study reveals decreased sigma‐1 receptor expression in Alzheimer's disease, offering a promising tool for ...
Ping Bai +12 more
wiley +1 more source
Opioid use Disorder for Prescription Opioid Medications
Global Journal of Addiction & Rehabilitation Medicine, 2017 Why are opioid medications prescribed in large quantities and high frequency when there is little or no proven efficacy for their therapeutic value? Why are opioids the most commonly prescribed medication in the United States for the past decades when the adverse consequences continue to grow and mount?
openaire +2 more sources
Addiction Science & Clinical Practice, 2022 Background Medications to treat opioid use disorder (OUD) including buprenorphine products are evidence-based and cost-effective tools for combating the opioid crisis.
Kevin P. Conway +5 more
doaj +1 more source
Intraoperative Dexmedetomidine Administration Effects on Postoperative Pain Scores and Opioid Medication Requirements: Pain Management Expectations Among CRNAs [PDF]
, 2022 Opioid pain medications are currently viewed as a standard part of pain control in the vast majority of surgical procedures. However, opioid pain medications can have harmful effects on patients leading to increased length of hospital stay, unplanned ...
Bodine, Matthew +2 more
core +1 more source
"Can We Detect Substance Use Disorder?": Knowledge and Time Aware Classification on Social Media from Darkweb [PDF]
arXiv, 2023 Opioid and substance misuse is rampant in the United States today, with the phenomenon known as the "opioid crisis". The relationship between substance use and mental health has been extensively studied, with one possible relationship being: substance misuse causes poor mental health.
arxiv
Advanced Science, EarlyView.Intratracheal neomycin alters pulmonary microbiota, activating the vagus nerve via lung brain‐derived neurotrophic factor/tropomyosin receptor kinase B (BDNF/TrkB) pathway, further projecting to nucleus of solitary tract (NTS), then dorsal raphe nucleus (DRN), where activated serotoninergic neurons increase brain serotonin, alleviating migraine.
Biying Liu +7 more
wiley +1 more source
Rapid Access to Medications for Opioid Use Disorder [PDF]
Journal of General Internal Medicine, 2021 Robert A. Kleinman, Nathaniel P. Morris
openaire +3 more sources
Barriers and Facilitators to the Use of Medications for Opioid Use Disorder: a Rapid Review [PDF]
Journal of General Internal Medicine, 2020 Despite evidence that medications to treat opioid use disorder (OUD) are effective, most people who could benefit from this treatment do not receive it. This rapid review synthesizes evidence on current barriers and facilitators to buprenorphine/naloxone and naltrexone at the patient, provider, and system levels to inform future interventions aimed at ...
Johanna Anderson +4 more
openaire +3 more sources
Rural and Remote HealthIntroduction: Rates of N-methylamphetamine (methamphetamine) use in rural areas of the US have been steadily increasing, particularly among individuals who are already struggling with opioid use disorder.
Leslie Kenefick +9 more
doaj +1 more source
Harm Reduction Journal, 2021 Background For people with opioid use disorder who are not responding to oral opioid agonist treatment, evidence supports the effectiveness of injectable opioid agonist treatment with injectable hydromorphone (an opioid analgesic) and diacetylmorphine ...
Heather Palis +3 more
doaj +1 more source