Results 71 to 80 of about 68,171 (350)

Confronting the opioid crisis: Practical pain management and strategies: AOA 2018 critical issues symposium [PDF]

, 2019
The United States is in the midst of an opioid crisis. Clinicians have been part of the problem because of overprescribing of narcotics for perioperative pain management.
Hsu, Joseph R, Jahangir, A Alex, Miller, Anna N, Mir, Hassan R, Obremskey, William T   +4 more
core   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Urine Screening for Opiod and Illicit Drugs in the Total Joint Arthroplasty Population [PDF]

, 2020
Introduction. Recent studies have shown an increase in post-operative orthopaedic complications associated with pre-operative opioid use. It is, therefore, important to know if patients use opioids before scheduled surgery.
Bhargava, Tarun, Messamore, William, Schmanke, Ken, Trent, Jesse, Vopat, Matthew, Yang, Shang-You, Zackula, Rosey   +6 more
core   +2 more sources

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Structural and social changes due to the COVID-19 pandemic and their impact on engagement in substance use disorder treatment services: a qualitative study among people with a recent history of injection drug use in Baltimore, Maryland

Harm Reduction Journal
Background Substance use disorder treatment and recovery support services are critical for achieving and maintaining recovery. There are limited data on how structural and social changes due to the COVID-19 pandemic impacted individual-level experiences ...
Eshan U. Patel, Suzanne M. Grieb, Abigail K. Winiker, Jennifer Ching, Catherine G. Schluth, Shruti H. Mehta, Gregory D. Kirk, Becky L. Genberg   +7 more
doaj   +1 more source

The challenge of perioperative pain management in opioid-tolerant patients [PDF]

, 2017
The increasing number of opioid users among chronic pain patients, and opioid abusers among the general population, makes perioperative pain management challenging for health care professionals.
Bifulco, F, Coluzzi, Flaminia, Corcione, A., Cuomo, A, Dauri, M, Leonardi, C, Melotti, Rm, Natoli, S, Romualdi, P, Savoia, G   +9 more
core   +2 more sources

Rapid and Direct Detection of Methamphetamine in Biofluids using a MXene‐Enabled Electrochemical Sensor

Advanced Science, EarlyView.
A MXene‐enhanced electrochemical sensor enables the rapid and direct detection of methamphetamine. Molecular simulations reveal that specific MXene surface functional groups act as key signal amplifiers by facilitating interfacial interactions. The sensor demonstrates high sensitivity and robust performance in complex biological matrices.
Ri Wang, Xiaofei Deng, Bo Chen, Jienan Shen, Wei Xu, Yingjie Zhu, Yi Zhang, Hui Yang   +7 more
wiley   +1 more source

Residential treatment and medication treatment for opioid use disorder: The role of state Medicaid innovations in advancing the field

Drug and Alcohol Dependence Reports, 2022
Background: Mortality due to opioid use continues to increase; effective strategies to improve access to treatment for opioid use disorder (OUD) are needed.
Peggy L. O'Brien, Maureen T. Stewart, Morgan C. Shields, Mackenzie White, Joel Dubenitz, Judith Dey, Norah Mulvaney-Day   +6 more
doaj   +1 more source

Housing First for People with Opioid Use disorder (OUD) and engagement with Medication-assisted Treatment (MAT) and Harm Reduction Services [PDF]

, 2020
Intro: Opioid Use Disorder (OUD)is one of the most prevalent and deadly SUD’s in the country and many barriers exist for individuals living with homelessness and concurrent psychiatric illnesses when hoping to engage in Medication-Assisted-Recovery ...
Katzenstein, Ashley, Siddiqui, Husayn, Weinstein, MD, DrPH, Lara   +2 more
core   +1 more source

A community‐driven approach to address substance use and create a Great Plains American Indian addiction and recovery research agenda

American Journal of Community Psychology, EarlyView.
Abstract Substance use, specifically opioid and methamphetamine use, is of increasing concern among American Indian (AI) populations in the Great Plains. This community‐driven participatory study investigated the impacts of substance use and community‐defined needs in treating addiction.
Brynn Luger, Anna Kihlström, Brinda Sivaramakrishnan, Allison Kelliher, Frankie Kropp, Carmen Rosa, T. John Winhusen, Donald Warne, the CTN0129 participating Tribal communities   +8 more
wiley   +1 more source