Results 1 to 10 of about 4,845 (133)
Gene-gene and gene-environment interactions of CYP19A1, ESR1, IL6, IL6R, IL1β, RANK, and RANKL variants in relation to osteoporosis and hip fracture risk in Mexican women [PDF]
Frontiers in AgingBackgroundOsteoporosis is a complex disease influenced by genetic variants, environmental factors, and comorbidities. While individual single-nucleotide variants (SNVs) have been associated with disease risk, limited data are available on how gene–gene ...
Antonio Miranda-Duarte +8 more
doaj +2 more sources
Serum Calcium Concentration Is Associated with Bone Mineral Density and Synonymous Variants in the RYR1 Gene in a Mexican-Mestizo Population [PDF]
Medical SciencesBackground/Objectives: Serum calcium concentrations have been associated with bone mineral density (BMD), but results seem to depend on sex. Genetic variants in the Ryanodine Receptor1 (RYR1) gene have been previously associated with low BMD in ...
Tania V. López-Pérez +10 more
doaj +2 more sources
Medicina genómica aspectos éticos, legales y sociales del genoma humano
Revista Latinoamericana de Bioética, 2011 La Medicina Genómica es el uso de la información de los genomas y sus derivados (ARN, proteínas y metabólicos) que permite guiar la toma de decisiones médicas, es un componente clave de la medicina personalizada.
Rodolfo E. Ávila +3 more
doaj +3 more sources
Revista Latinoamericana de Bioética, 2011 La medicina genómica y sus diferentes formas de aplicación medicinas personalizada o individualizada, de la que hacen parte la farmacogenómica, toxicogenómica y nutrigenómica; y la medicina predictiva, regenerativa o de reemplazo, molecular y ...
Ana Isabel Gómez Córdoba
doaj +3 more sources
Adipocyte, 2021 Adipogenesis regulation is crucial for mature adipocyte function. In obesity, a major driver of type 2 diabetes (T2D), this process is disrupted and remains poorly characterized.
Elaheh Mirzaeicheshmeh +11 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2021 Next Generation Sequencing has identified many KCNQ1 genetic variants associated with type 1 long QT or Romano-Ward syndrome, most frequently inherited in an autosomal dominant fashion, although recessive forms have been reported.
Antonia González-Garrido +9 more
doaj +1 more source
Transcriptional identification of genes light-interacting in the extraretinal photoreceptors of the crayfish Procambarus clarkii [PDF]
ZooKeys, 2021 Crayfish serve as a model for studying the effect of environmental lighting on locomotor activity and neuroendocrine functions. The effects of light on this organism are mediated differentially by retinal and extraretinal photoreceptors located in the ...
Gabina Calderón-Rosete +5 more
doaj +3 more sources
Educación Química, 2018 Durante los últimos veinte años el mundo ha sido testigo de cómo los científicos descifraron la secuencia del genoma humano y desarrollaron estrategias para estudiar extensivamente la diversidad genética, el desequilibrio del ligamiento (LD por sus ...
Irma Silva Zolezzi
doaj +1 more source
Metabolic syndrome in indigenous communities in Mexico: a descriptive and cross-sectional study
BMC Public Health, 2020 Background An Amerindian genetic background could play an important role in susceptibility to metabolic diseases, which have alarmingly increased in recent decades. Mexico has one of the highest prevalences of metabolic disease worldwide.
Elvia Cristina Mendoza-Caamal +17 more
doaj +1 more source
Nature Communications, 2021 Indigenous populations, including in those in Mexico are underrepresented in genetic studies. Here, the authors perform a population genetics study of indigenous peoples in Mexico to explore demographic histories of the region in the context of geography
Humberto García-Ortiz +39 more
doaj +1 more source