Results 21 to 30 of about 4,845 (133)
The FEBS Journal, EarlyView.MRTFs and YAP/TAZ proteins, or mechanosensitive transcriptional cofactors (MRTcoF), regulate common genes associated with cellular contractility and immune cell infiltration. Their differential regulation in response to stiffness is linked to changes in hepatocyte's aspect ratio. MRTFB does not undergo nuclear translocation under these conditions. This
Brenda Selene Torres‐Ortiz +13 more
wiley +1 more source
Plant, Cell &Environment, Volume 49, Issue 9, Page 7168-7190, September 2026.ABSTRACT Volatile organic compounds (VOCs) emitted by certain fungi have previously been suggested to modulate plant development and their response to stresses. While some fungal species, such as Trichoderma harzianum, are known to produce VOCs, the production of VOCs in other phylogenetically divergent species, such as Mucor mucedo, was previously ...
Sara Yugueros +7 more
wiley +1 more source
Avanzando hacia la medicina genómica para la atención de salud mental en Chile
ARS MedicaActualmente, las aplicaciones de la medicina genómica son una realidad para múltiples problemas clínicos, gracias al progreso de las tecnologías que permiten la secuenciación genética para establecer diagnósticos y tomar decisiones sobre tratamientos ...
M. Leonor Bustamante Calderón +2 more
doaj +1 more source
Aging Cell, Volume 25, Issue 8, August 2026.We demonstrated that progerin induces the formation of autophagosomes but impairs their maturation and subsequent fusion with lysosomes. Progerin impedes proper autophagy flux, thus preventing its own autophagic degradation. Selinexor treatment improved both autophagosome maturation and autophagosome‐lysosome fusion, which ultimately led to effective ...
Ian García‐Aguirre +18 more
wiley +1 more source
BMC Genetics, 2019 Background Association studies are useful to unravel the genetic basis of common human diseases. However, the presence of undetected population structure can lead to both false positive results and failures to detect genuine associations.
Alicia Huerta-Chagoya +11 more
doaj +1 more source
Pathogens, 2022 The performance and validity of the COVISTIXTM rapid antigen test for the detection of SARS-CoV-2 were evaluated in an unselected population. Additionally, we assessed the influence of the Omicron SARS-CoV-2 variant in the performance of this antigen ...
Francisco Garcia-Cardenas +11 more
doaj +1 more source
Salud Pública de México, 2013 OBJETIVO: Explorar las perspectivas de los investigadores en medicina genómica y cómo incide esta última en las políticas de salud en México. MATERIAL Y MÉTODOS: Se realizó una investigación cualitativa a partir de entrevistas semiestructuradas, durante ...
Pablo Francisco Oliva-Sánchez +4 more
doaj
An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids
Advanced Materials Technologies, Volume 11, Issue 14, 22 July 2026.This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto +6 more
wiley +1 more source
Quantitative Control of Transposable Elements: From Genome Plasticity to Immune Regulatory Circuits
Cell Biochemistry and Function, Volume 44, Issue 7, July 2026.ABSTRACT Transposable elements (TEs) constitute nearly half of the human genome and are increasingly recognized as context‐dependent regulators of genome function rather than passive repetitive DNA. This Review synthesizes classical and recent evidence on TE biology, including TE classification, mechanisms of mobilization, host restriction pathways ...
Irving Jesús Reyes‐Barragán
wiley +1 more source
Current Issues in Molecular Biology, 2022 Osteoporosis (OP) is the most common bone disease affecting elderly individuals. The diagnosis of this pathology is most commonly made on the basis of bone fractures.
Eric Gustavo Ramírez-Salazar +5 more
doaj +1 more source