Results 71 to 80 of about 179,125 (263)

Metabolism and signaling crosstalk in glioblastoma progression and therapy resistance

open access: yesMolecular Oncology, Volume 19, Issue 3, Page 592-613, March 2025.
Glioblastoma is one of the most lethal human cancers with no effective treatment nowadays. Here, we review the increasing amount of evidence supporting the connection between cell signaling deregulation and metabolic reprogramming as a key event in glioblastoma resistance to cancer therapy.
Laura Zarzuela   +2 more
wiley   +1 more source

La medicina genómica un cambio de paradigma de la medicina moderna. Retos para la bioética y el derecho

open access: yesRevista Latinoamericana de Bioética, 2011
La medicina genómica y sus diferentes formas de aplicación medicinas personalizada o individualizada, de la que hacen parte la farmacogenómica, toxicogenómica y nutrigenómica; y la medicina predictiva, regenerativa o de reemplazo, molecular y ...
Ana Isabel Gómez Córdoba
doaj   +3 more sources

La ingeniería biomédica en la UC3M [PDF]

open access: yes, 2014
Los rankings profesionales en las proyecciones del Departamento de Trabajo del gobierno de EE.UU. para el periodo 2008-2018, publicaba en 2010 la lista de las 50 carreras que, en su opinión, ofrecían las mejores oportunidades: en el área de ciencia y ...
Jorcano, José L.
core   +1 more source

Transcriptomic analysis reveals the participation of NTRC in iron homeostasis in Arabidopsis

open access: yesPhysiologia Plantarum, Volume 177, Issue 2, March/April 2025.
Abstract NADPH‐dependent thioredoxin reductase C (NTRC) plays a central role in redox regulation of chloroplast photosynthetic metabolism. Accordingly, Arabidopsis (Arabidopsis thaliana) NTRC‐null mutants show defective photosynthetic performance and growth inhibition.
Fernando Rodríguez‐Marín   +2 more
wiley   +1 more source

Intranasal mesenchymal stem cell secretome administration markedly inhibits alcohol and nicotine self-administration and blocks relapse-intake: mechanism and translational options

open access: yesStem Cell Research & Therapy, 2019
Background Chronic consumption of most drugs of abuse leads to brain oxidative stress and neuroinflammation, which inhibit the glutamate transporter GLT-1, proposed to perpetuate drug intake.
María Elena Quintanilla   +7 more
doaj   +1 more source

Nanotecnologías dirigidas a necesidades sociales. Contribuciones de la investigación latinoamericana en medicina, energía y agua [PDF]

open access: yes, 2015
Este artículo examina, con base en informaciones provenientes de publicaciones científicas y grupos de investigación, el estado de la investigación en nanotecnología aplicada a las áreas de medicina, energía y agua en América Latina. Tales áreas han sido
Arteaga Figueroa, Edgar Ramón   +8 more
core   +1 more source

Spontaneous Self‐Organized Order Emerging From Intrinsically Disordered Protein Polymers

open access: yesWIREs Nanomedicine and Nanobiotechnology, Volume 17, Issue 1, January/February 2025.
Harnessing the liquid‐liquid phase separation (LLPS) properties of intrinsically disordered protein polymers (IDPPs) enables the design and engineering of hierarchically self‐assembled protein materials with customizable structures and increasing complexity.
Sergio Acosta   +4 more
wiley   +1 more source

Omental adipose tissue is a more suitable source of canine Mesenchymal stem cells

open access: yesBMC Veterinary Research, 2017
Background Mesenchymal Stem Cells (MSCs) are a promising therapeutic tool in veterinary medicine. Currently the subcutaneous adipose tissue is the leading source of MSCs in dogs.
Francisca Bahamondes   +4 more
doaj   +1 more source

Maintenance of chronicity signatures in fibroblasts isolated from recessive dystrophic epidermolysis bullosa chronic wound dressings under culture conditions

open access: yesBiological Research, 2023
Background Recessive Dystrophic Epidermolysis Bullosa (RDEB) is a rare inherited skin disease caused by variants in the COL7A1 gene, coding for type VII collagen (C7), an important component of anchoring fibrils in the basement membrane of the epidermis.
Cristian De Gregorio   +16 more
doaj   +1 more source

Diabetic nephropathy, autophagy and proximal tubule protein endocytic transport: A potentially harmful relationship [PDF]

open access: yes, 2018
Diabetic nephropathy (DN) is the most frequent cause of chronic renal failure. Until now, the pathophysiological mechanisms that determine its development and progression have not yet been elucidated.
Agüero, Rocio   +4 more
core  

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