Results 71 to 80 of about 782,998 (207)

Metabolism and signaling crosstalk in glioblastoma progression and therapy resistance

open access: yesMolecular Oncology, Volume 19, Issue 3, Page 592-613, March 2025.
Glioblastoma is one of the most lethal human cancers with no effective treatment nowadays. Here, we review the increasing amount of evidence supporting the connection between cell signaling deregulation and metabolic reprogramming as a key event in glioblastoma resistance to cancer therapy.
Laura Zarzuela   +2 more
wiley   +1 more source

Transcriptomic analysis reveals the participation of NTRC in iron homeostasis in Arabidopsis

open access: yesPhysiologia Plantarum, Volume 177, Issue 2, March/April 2025.
Abstract NADPH‐dependent thioredoxin reductase C (NTRC) plays a central role in redox regulation of chloroplast photosynthetic metabolism. Accordingly, Arabidopsis (Arabidopsis thaliana) NTRC‐null mutants show defective photosynthetic performance and growth inhibition.
Fernando Rodríguez‐Marín   +2 more
wiley   +1 more source

Formation of 53BP1 foci and ATM activation under oxidative stress is facilitated by RNA:DNA hybrids and loss of ATM-53BP1 expression promotes photoreceptor cell survival in mice [version 1; referees: 1 approved, 2 approved with reservations]

open access: yesF1000Research, 2018
Background: Photoreceptors, light-sensing neurons in retina, are central to vision. Photoreceptor cell death (PCD) is observed in most inherited and acquired retinal dystrophies. But the underlying molecular mechanism of PCD is unclear.
Vaibhav Bhatia   +3 more
doaj   +1 more source

Medicina regenerativa en enfermedades músculo-esqueléticas, terapias actuales y visiones de futuro: una revisión sistemática. [PDF]

open access: yes, 2020
La pérdida de órganos y tejidos debido a enfermedades y lesiones ha motivado el desarrollo de terapias que pueden regenerar tejidos y disminuir la dependencia de trasplantes.
Rodríguez Barrios, Pablo
core  

Medicina regenerativa en estomatología

open access: yes, 2014
Introduction: Nowadays, one of the most outstanding medical issues is to regenerative medicine and in particular stem cells, which has been described as a new scientific and technological revolution.Objective: to review the literature on applications of ...
Morales Navarro, Denia
core  

Estatuts de la Fundació Centre de Medicina Regenerativa de Barcelona [2012 text no oficial]

open access: yes, 2012
Aprovats pel Patronat de la Fundació de 14-12 ...
Fundació Centre de Medicina Regenerativa de Barcelona
core   +1 more source

La medicina regenerativa frente a la medicina convencional

open access: yes, 2022
4 páginasEl paso del tiempo y la historia han sido testigos de cómo diversos ámbitos de la vida han cambiado y evolucionado, una clara muestra de esto es la medicina, que ha experimentado diversas variaciones llevándola a lo que se conoce actualmente ...
Cortés Amaya, Sara Sofía
core   +1 more source

Rpd3L and Hda1 histone deacetylases facilitate repair of broken forks by promoting sister chromatid cohesion

open access: yesNature Communications, 2019
Double strand breaks (DSBs) are preferentially repaired by sister-chromatid recombination (SCR) to maintain genome stability. Here, the authors reveal a role for histone deacetylate (HDAC) complexes favouring the repair of replication related DSBs by ...
Pedro Ortega   +2 more
doaj   +1 more source

Gene gating at nuclear pores prevents the formation of R loops

open access: yesMolecular & Cellular Oncology, 2018
Transcription is an important source of genetic variability. A large amount of transcription-associated genome variation arises from the unscheduled formation of R loops.
Hélène Gaillard   +2 more
doaj   +1 more source

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