Results 61 to 70 of about 782,998 (207)

Transcription‐Replication Conflicts: Unlocking New Frontiers in Cancer

BioEssays, Volume 47, Issue 8, August 2025.
Transcription‐replication conflicts (TRCs) constitute a major source of genome instability. Such conflicts are regulated by chromatin, its dysfunction causing replication stress, DNA breaks, and mutations frequently found in cancer. We review the molecular basis of TRCs and chromatin regulation and discuss the clinical potential of targeting TRCs as ...
Aleix Bayona‐Feliu, Andrés Aguilera
wiley   +1 more source

Organóides : o futuro da medicina dentária regenerativa?

, 2021
Introdução: Ao longo dos últimos anos têm sido realizados diversos procedimentos experimentais para avaliar a viabilidade da utilização de estruturas biológicas tridimensionais, complexas e auto-organizadas, recriando a arquitetura e a função de órgãos nativos in vivo, na região oral e maxilofacial.
openaire   +2 more sources

The role of the endogenous opioid system in modulating orthodontic‐induced neurogenic inflammation of the dental pulp: A comprehensive review of the literature

International Endodontic Journal, Volume 58, Issue 8, Page 1126-1145, August 2025.
Abstract Background Orthodontic forces may lead to neurogenic inflammation in the dental pulp by triggering the release of somatosensory neuropeptides such as Substance P (SP), Calcitonin gene‐related peptide (CGRP) and Neurokinin A (NKA). In the vast majority of patients, acute symptoms are not triggered, probably due to the control of the neurogenic ...
Javier Caviedes‐Bucheli, Nestor Rios‐Osorio, Esteban Ulate‐Rodríguez, Hernan Dario Muñoz‐Alvear, José F. Gaviño‐Orduña, P. Sebastian Ortolani‐Seltenerich, Jose F. Gomez‐Sosa, Hugo Roberto Munoz   +7 more
wiley   +1 more source

Terapia regenerativa en hipoacusia neurosensorial [PDF]

, 2021
Según la Organización Mundial de la Salud, la hipoacusia afecta a más de 400 millones de personas en el mundo. Actualmente, el tratamiento para la hipoacusia neurosensorial se basa en la colocación de audífonos e implantes cocleares con una ...
Vegas Reynolds, Mónica
core  

Desarrollo de la Medicina Regenerativa Periodontal con células madre y hemocomponentes

Medimay, 2023
Cuba, es uno de los países con una notable aplicación de la medicina celular regenerativa, en especialidades médicas y estomatológicas, Santiago de Cuba, ha contribuido a su desarrollo, en los últimos años.
Maritza Peña Sisto, Rosa Julia Robinson Rodríguez, Niurka Aurora Alí Pérez   +2 more
doaj  

Omental adipose tissue is a more suitable source of canine Mesenchymal stem cells

BMC Veterinary Research, 2017
Background Mesenchymal Stem Cells (MSCs) are a promising therapeutic tool in veterinary medicine. Currently the subcutaneous adipose tissue is the leading source of MSCs in dogs.
Francisca Bahamondes, Estefania Flores, Gino Cattaneo, Flavia Bruna, Paulette Conget   +4 more
doaj   +1 more source

Biohybrid Vascular Graft Made of Textile‐Reinforced Elastin‐Like Recombinamers and Its Preservation via Drying Processes

Advanced Healthcare Materials, Volume 14, Issue 15, 10 June, 2025.
Clinical translation of biohybrid medical implants requires the previous implementation of drying schemes that can facilitate their sterilization and storage. This study addresses that critical aspect and elucidates the impact of drying on biohybrid vascular grafts, highlighting the need for implant‐specific drying strategies to ensure safety ...
Dominic Pascal Andre, Stephan Ruetten, José Carlos Rodríguez‐Cabello, Stefan Jockenhoevel, Thomas Schmitz‐Rode, Alicia Fernández‐Colino   +5 more
wiley   +1 more source

The CDK12–BRCA1 signaling axis mediates dinaciclib‐associated radiosensitivity through p53‐mediated cellular senescence

Molecular Oncology, Volume 19, Issue 4, Page 1265-1280, April 2025.
Dinaciclib blocks CDK12 activity, leading to downregulation of BRCA1, and probably other proteins involved in homologous recombination, promoting nonhomologous end joining. In this scenario, the presence of ionising radiation triggers a p53‐dependent senescent response that yields increased radiosensitivity. Pan‐cyclin‐dependent‐kinase (CDK) inhibitors
Natalia García Flores, Diego M. Fernández‐Aroca, Cristina Garnés‐García, Andrés Domínguez‐Calvo, Jaime Jiménez‐Suárez, Sebastià Sabater, Pablo Fernández‐Aroca, Ignacio Andrés, Francisco J. Cimas, Guillermo de Cárcer, Borja Belandia, Ignacio Palmero, Pablo Huertas, María José Ruiz‐Hidalgo, Ricardo Sánchez‐Prieto   +14 more
wiley   +1 more source

Aportes de la ciencia de materiales a la medicina regenerativa

, 2014
En este articulo se definen los alcances de la ciencia e ingeniería de biomateriales y la ingeniería de tejidos o medicina regenerativa, teniendo en cuenta la notable evolución que estos campos multidisciplinarios han experimentado en los últimos años ...
Abraham, Gustavo Abel
core   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source