Results 51 to 60 of about 169,494 (250)

Terapia regenerativa en hipoacusia neurosensorial [PDF]

open access: yes, 2021
Según la Organización Mundial de la Salud, la hipoacusia afecta a más de 400 millones de personas en el mundo. Actualmente, el tratamiento para la hipoacusia neurosensorial se basa en la colocación de audífonos e implantes cocleares con una ...
Vegas Reynolds, Mónica
core  

Personalized Cancer Vaccines in the Clinical Trial Pipeline

open access: yesAsia-Pacific Journal of Clinical Oncology, Volume 22, Issue 3, Page 362-368, June 2026.
ABSTRACT Aim To present an overview of personalized cancer vaccines currently undergoing clinical development, aiming to enhance awareness and promote collaboration among academic, commercial researchers, and non‐profit communities. Methods A dataset of 78 clinical trials for personalized cancer vaccines was generated using ClinicalTrials.gov database ...
Liudmila Iamukova, Elena Alferova
wiley   +1 more source

A Versatile Engineering Platform for the Fabrication of Prosthetic Venous Valves Using Electrospinning

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 16, 24 April 2026.
Percutaneous prosthetic venous valves are fabricated by embedding stents in an electrospun matrix that extends luminally to form leaflets. The design shields leaflets from hyperplastic cells, isolates struts from blood contact, and avoids discrete anchoring points.
Dario Arcuti   +6 more
wiley   +1 more source

The role of bone marrow mononuclear cell-conditioned medium in the proliferation and migration of human dermal fibroblasts

open access: yesCellular & Molecular Biology Letters, 2017
Background Several recent studies have demonstrated the great potential of bone marrow cells in regenerative medicine, not only for their ability to differentiate to match a damaged cell type, but also because they synthesize and release various growth ...
Yolanda Menéndez-Menéndez   +6 more
doaj   +1 more source

Histone H3E73Q and H4E53A mutations cause recombinogenic DNA damage

open access: yesMicrobial Cell, 2020
The stability and function of eukaryotic genomes is closely linked to histones and to chromatin structure. The state of the chromatin not only affects the probability of DNA to undergo damage but also DNA repair.
Pedro Ortega   +5 more
doaj   +1 more source

Decidualized human decidual stromal cells inhibit chemotaxis of activated T cells: a potential mechanism of maternal-fetal immune tolerance

open access: yesFrontiers in Immunology, 2023
BackgroundNumerous lines of evidence confirm that decidual stromal cells (DSCs) play a key role in maternal–fetal immune tolerance. Under the influence of progesterone and other hormones, the DSCs go through a process of differentiation (decidualization)
Tatiana Llorca   +11 more
doaj   +1 more source

Prolonged Release of IL‐10 From Enzyme‐Mediated Poly‐l‐(Tyrosine‐co‐Phenylalanine) Nanocrystals Enhances Stability and Modulates Inflammatory Responses

open access: yesBiopolymers, Volume 117, Issue 2, March 2026.
Schematic representation of enzyme‐mediated peptide nanocrystal formation and IL‐10 encapsulation, providing stabilized and sustained cytokine delivery that modulates macrophage phenotype and reduces inflammatory responses. ABSTRACT Protease‐catalyzed synthesis of a peptide composed of l‐tyrosine and l‐phenylalanine (2.2:1 M ratio) was achieved in a ...
Fátima Landa‐Tencle   +11 more
wiley   +1 more source

La medicina regenerativa frente a la medicina convencional

open access: yes, 2022
El paso del tiempo y la historia han sido testigos de cómo diversos ámbitos de la vida han cambiado y evolucionado, una clara muestra de esto es la medicina, que ha experimentado diversas variaciones llevándola a lo que se conoce actualmente.
Cortés Amaya, Sara Sofía
core   +1 more source

Harmful DNA:RNA hybrids are formed in cis and in a Rad51-independent manner

open access: yeseLife, 2020
DNA:RNA hybrids constitute a well-known source of recombinogenic DNA damage. The current literature is in agreement with DNA:RNA hybrids being produced co-transcriptionally by the invasion of the nascent RNA molecule produced in cis with its DNA template.
Juan Lafuente-Barquero   +4 more
doaj   +1 more source

TGF-β-Upregulated Lnc-Nr6a1 Acts as a Reservoir of miR-181 and Mediates Assembly of a Glycolytic Complex

open access: yesNon-Coding RNA, 2022
Long non-coding RNAs (lncRNAs) have emerged as key regulators in a wide range of biological processes. Here, we identified a mouse miRNA-host gene lncRNA (Lnc-Nr6a1) upregulated early during epithelial-to-mesenchymal transition (EMT).
Salvador Polo-Generelo   +6 more
doaj   +1 more source

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