Results 31 to 40 of about 169,494 (250)

Reflexiones en torno a la aplicación de las celulas madre en la Medicina Regenerativa

open access: yesRevista Habanera de Ciencias Médicas, 2005
Con fines de divulgación científica se abordaron aspectos de la revolución actual en Biomedicina que conducen a la clonación; se enfatizó en las repercusiones de su vertiente terapéutica en la cirugía cardiaca con transplantes celulares y el desarrollo ...
Tomás Ariel Lombardo Vaillant
doaj   +2 more sources

Systemically administered allogeneic mesenchymal stem cells do not aggravate the progression of precancerous lesions: a new biosafety insight

open access: yesStem Cell Research & Therapy, 2018
Background Mesenchymal stem cells (MSCs) are a heterogeneous subset of stromal cells currently tested for multiple therapeutic purposes. Their potential to home into tumors, to secrete trophic/vasculogenic factors, and to suppress immune response raises ...
Flavia Bruna   +4 more
doaj   +1 more source

Novel insights into the roles of Cdc7 in response to replication stress

open access: yesThe FEBS Journal, Volume 290, Issue 12, Page 3076-3088, June 2023., 2023
Cdc7 and its regulator Dbf4 (Dbf4‐dependent kinase; DDK) is an essential complex due to its function in replication initiation. Evidence from yeast to human shows that Cdc7 is also required for a successful DNA damage response by coordinating multiple processes dealing with replication stress such as stalled fork protection, translesion synthesis (TLS),
Cristina González‐Garrido   +1 more
wiley   +1 more source

Functional Properties of Human-Derived Mesenchymal Stem Cell Spheroids: A Meta-Analysis and Systematic Review

open access: yesStem Cells International, 2021
Mesenchymal stem cells (MSC) are adult multi-potent cells that can be isolated from many types of tissues including adipose tissue, bone marrow, and umbilical cord.
Sarah Ezquerra   +5 more
doaj   +1 more source

Limiting glutamine utilization activates a GCN2/TRAIL-R2/Caspase-8 apoptotic pathway in glutamine-addicted tumor cells

open access: yesCell Death and Disease, 2022
Oncogenic transformation leads to changes in glutamine metabolism that make transformed cells highly dependent on glutamine for anabolic growth and survival.
Rosario Yerbes   +5 more
doaj   +1 more source

Biohybrid Vascular Graft Made of Textile-Reinforced Elastin-Like Recombinamers and Its Preservation via Drying Processes. [PDF]

open access: yesAdv Healthc Mater
Clinical translation of biohybrid medical implants requires the previous implementation of drying schemes that can facilitate their sterilization and storage. This study addresses that critical aspect and elucidates the impact of drying on biohybrid vascular grafts, highlighting the need for implant‐specific drying strategies to ensure safety ...
Andre DP   +5 more
europepmc   +2 more sources

Type I collagen hydrogels as a delivery matrix for royal jelly derived extracellular vesicles

open access: yesDrug Delivery, 2020
Throughout the last decade, extracellular vesicles (EVs) have become increasingly popular in several areas of regenerative medicine. Recently, Apis mellifera royal jelly EVs (RJ EVs) were shown to display favorable wound healing properties such as ...
Orlando J. Ramírez   +5 more
doaj   +1 more source

Plasma concentrations of granulocyte colony-stimulating factor (G-CSF) in patients with substance use disorders and comorbid major depressive disorder

open access: yesScientific Reports, 2021
Granulocyte colony–stimulating factor (G-CSF) has raised much interest because of its role in cocaine addiction in preclinical models. We explored the plasma concentrations of G-CSF in patients diagnosed with substance use disorder (SUD) and highly ...
Sandra Torres Galván   +12 more
doaj   +1 more source

Relações ‘biossociais’: as associações de pacientes e a medicina regenerativa no Brasil

open access: yesRevista tecnología y sociedad, 2022
As associações de pacientes têm surgido como lócus privilegiado para mediar a relação entre o Estado e a Sociedade. O estudo analisa seu papel em relação à medicina regenerativa no Brasil, priorizando as associações de pacientes com doenças raras ...
L. Acero
semanticscholar   +1 more source

Potencialidad Celular Evolutiva y Medicina Regenerativa [PDF]

open access: yesInternational Journal of Morphology, 2012
Las celulas derivadas del embrioblasto o macizo celular interno (MCI) del blastocisto corresponden a las celulas madres embrionarias, ellas son pluripotentes, debido a que tienen la capacidad de generar todas las estirpes celulares y al resto, se les conoce como celulas madres adultas porque tienen un potencial de diferenciacion mucho mas restringido ...
Rojas, Mariana, Meruane, Manuel
openaire   +2 more sources

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