Results 31 to 40 of about 767,779 (167)

Harmful DNA:RNA hybrids are formed in cis and in a Rad51-independent manner

eLife, 2020
DNA:RNA hybrids constitute a well-known source of recombinogenic DNA damage. The current literature is in agreement with DNA:RNA hybrids being produced co-transcriptionally by the invasion of the nascent RNA molecule produced in cis with its DNA template.
Juan Lafuente-Barquero, Maria Luisa García-Rubio, Marta San Martin-Alonso, Belén Gómez-González, Andrés Aguilera   +4 more
doaj   +1 more source

Decidualized human decidual stromal cells inhibit chemotaxis of activated T cells: a potential mechanism of maternal-fetal immune tolerance

Frontiers in Immunology, 2023
BackgroundNumerous lines of evidence confirm that decidual stromal cells (DSCs) play a key role in maternal–fetal immune tolerance. Under the influence of progesterone and other hormones, the DSCs go through a process of differentiation (decidualization)
Tatiana Llorca, Maria Jose Ruiz-Magaña, Rocio Martinez-Aguilar, Olga María García-Valdeavero, Lucia Rodríguez-Doña, Ana Clara Abadia-Molina, Ana Clara Abadia-Molina, Carmen Ruiz-Ruiz, Carmen Ruiz-Ruiz, Enrique G. Olivares, Enrique G. Olivares, Enrique G. Olivares   +11 more
doaj   +1 more source

TGF-β-Upregulated Lnc-Nr6a1 Acts as a Reservoir of miR-181 and Mediates Assembly of a Glycolytic Complex

Non-Coding RNA, 2022
Long non-coding RNAs (lncRNAs) have emerged as key regulators in a wide range of biological processes. Here, we identified a mouse miRNA-host gene lncRNA (Lnc-Nr6a1) upregulated early during epithelial-to-mesenchymal transition (EMT).
Salvador Polo-Generelo, Belén Torres, José A. Guerrero-Martínez, Emilio Camafeita, Jesús Vázquez, José C. Reyes, José A. Pintor-Toro   +6 more
doaj   +1 more source

Medicina regenerativa en enfermedades músculo-esqueléticas, terapias actuales y visiones de futuro: una revisión sistemática. [PDF]

, 2020
La pérdida de órganos y tejidos debido a enfermedades y lesiones ha motivado el desarrollo de terapias que pueden regenerar tejidos y disminuir la dependencia de trasplantes.
Rodríguez Barrios, Pablo
core  

Revista Latinoamericana de Ginecología Regenerativa 1(1) 2023

, 2023
Misión La Revista Latinoamericana de Ginecología Regenerativa tiene la misión el generar, discutir y difundir investigaciones, conocimientos, documentos y demás información en Ginecología Regenerativa y áreas afines, para que esté al alcance de ...
Sociedad de Ginecología Regenerativa
core   +1 more source

Medicina regenerativa

Oncología, 2006
En la última década se han llevado a cabo grandes avances en diferentes ramas biomédicas, entre ellas la Biología Celular. Esto ha dado un notable impulso a una nueva rama de la Medicina denominada Medicina Regenerativa.
Bella Maldonado
doaj  

Las células mesenquimales y sus vesículas extracelulares. Una propuesta alterna en el manejo inmunoregulador y regenerativo en pacientes con psoriasis

Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica
La psoriasis es una enfermedad crónica inflamatoria que afecta el 2 a 3 % de la población mundial, se produce por una activación anormal del sistema inmune principalmente por las vía IL23 / Th17 y la IL12 /Th1 generando una hiperproliferación de los ...
Luz Mabel Avila Portillo, Laura Ximena Rojas-Arévalo, Luis Antonio Castro   +2 more
doaj   +1 more source

Both CD133 Cells and Monocytes Provide Significant Improvement for Hindlimb Ischemia, Although They do not Transdifferentiate Into Endothelial Cells

Cell Transplantation, 2010
To address a number of questions regarding the experimental use of bone marrow (BM) stem cells in hindlimb ischemia, including which is the best cell type (e.g., purified hematopoietic stem cell or monocytes), the best route of delivery [intramuscular ...
Fermin M. Sanchez-Guijo M.D., PhD., Enrique Oterino, Maria-Victoria Barbado, Soraya Carrancio, Natalia Lopez-Holgado, Sandra Muntion, Pilar Hernandez-Campo, Luis-Ignacio Sanchez-Abarca, Jose A. Perez-Simon, Jesús F. San Miguel, Jesús G. Briñon, Maria-Consuelo Del Cañizo   +11 more
doaj   +1 more source

Role of the YAP/TAZ-TEAD Transcriptional Complex in the Metabolic Control of TRAIL Sensitivity by the Mevalonate Pathway in Cancer Cells

Cells, 2023
Different studies have reported that inhibiting the mevalonate pathway with statins may increase the sensitivity of cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), although the signaling mechanism leading to this ...
Younes El Yousfi, Rocío Mora-Molina, Abelardo López-Rivas, Rosario Yerbes   +3 more
doaj   +1 more source

Radiobiology studies of gold nanoparticle‐enhanced radiosensitization in proton therapy

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background Approximately 50%$\%$ of newly diagnosed cancer patients worldwide receive radiotherapy, most commonly with X‐rays. Proton therapy has emerged as a promising alternative, offering complementary advantages over conventional X‐rays due to its highly localized energy deposition at the Bragg peak, thereby reducing radiation exposure to ...
N. Fuster‐Martínez, D. H. Saucedo‐Cuberes, M. C. Jiménez‐Ramos, D. Esperante, J. M. Espino, J. Fuster, J. F. Belén‐Aguilar, L. González‐López, P. Huertas, S. Jimeno, I. Mingarro, D. Pascual, D. Suárez‐García, M. J. García‐Murria   +13 more
wiley   +1 more source