Results 21 to 30 of about 1,649 (176)

Bioinductive collagen implants facilitate tendon regeneration in rotator cuff tears

Journal of Experimental Orthopaedics, 2022
Purpose To evaluate the clinical outcomes, MRI imaging and histological characteristics of biopsy samples of the tendon from patients in whom rotator cuff repair was previously performed with a bioinductive type I bovine collagen implants.
Jorge Alberto Camacho‐Chacon, Jorge Cuenca‐Espierrez, Victor Roda‐Rojo, Adrian Martin‐Martinez, Jose Manuel Calderon‐Meza, Ramiro Alvarez‐Alegret, Carlos Martin‐Hernandez   +6 more
doaj   +1 more source

Temporomandibular joint regeneration: proposal of a novel treatment for condylar resorption after orthognathic surgery using transplantation of autologous nasal septum chondrocytes, and the first human case report

Stem Cell Research & Therapy, 2018
Background Upon orthognathic mandibular advancement surgery the adjacent soft tissues can displace the distal bone segment and increase the load on the temporomandibular joint causing loss of its integrity.
Ricardo de Souza Tesch, Esther Rieko Takamori, Karla Menezes, Rosana Bizon Vieira Carias, Cláudio Leonardo Milione Dutra, Marcelo de Freitas Aguiar, Tânia Salgado de Sousa Torraca, Alexandra Cristina Senegaglia, Cármen Lúcia Kuniyoshi Rebelatto, Debora Regina Daga, Paulo Roberto Slud Brofman, Radovan Borojevic   +11 more
doaj   +1 more source

DNA-RNA hybrids at DSBs interfere with repair by homologous recombination

eLife, 2021
DNA double-strand breaks (DSBs) are the most harmful DNA lesions and their repair is crucial for cell viability and genome integrity. The readout of DSB repair may depend on whether DSBs occur at transcribed versus non-transcribed regions.
Pedro Ortega, José Antonio Mérida-Cerro, Ana G Rondón, Belén Gómez-González, Andrés Aguilera   +4 more
doaj   +1 more source

Medicina Regenerativa em dor crónica: entre o potencial transformador e os desafios da implementação

Revista Dor
A Medicina Regenerativa tem-se destacado como abordagem promissora no tratamento da Dor Crónica, permitindo não só o alívio dos sintomas, mas também a possibilidade de modificar o curso natural da doença.
Nuno Ferreira-Silva, Tomás Ribeiro-da-Silva, Rita Ribas   +2 more
doaj   +1 more source

Biomateriales para medicina regenerativa

Materiales Avanzados
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María Cristina Piña Barba, Israel Alfonso Núñez Tapia, David Eduardo Abad Contreras, Ángela Miscli Rangel García, Daniel Michell Padilla Ramos, Ricardo Mercurio Jiménez Jiménez, Luis Ariel Ruiz García   +6 more
openaire   +1 more source

BRCA1 Accelerates CtIP-Mediated DNA-End Resection

Cell Reports, 2014
DNA-end resection is a highly regulated and critical step in the response and repair of DNA double-strand breaks. In higher eukaryotes, CtIP regulates resection by integrating cellular signals via its posttranslational modifications and protein-protein ...
Andrés Cruz-García, Ana López-Saavedra, Pablo Huertas   +2 more
doaj   +1 more source

Uso de la medicina regenerativa en Odontología

Revista Arbitrada Interdisciplinaria de Ciencias de la Salud. Salud y Vida, 2022
Objetivo: De esta revisión bibliográfica será sintetizar y sistematizar la información actualizada sobre las técnicas y potenciales usos de la medicina regenerativa en el campo de la odontología. Método: Búsqueda bibliográfica en diferentes bases de datos como PubMed y Scielo.
Marco Antonio Mesache-Villagómez, Gabriela Vaca-Altamirano   +1 more
openaire   +1 more source

Biopolímeros: Aplicaciones de andamios en medicina regenerativa

Anatomía Digital, 2021
Los biopolímeros se han convertido en un herramienta indispensable para el desarrollo de la medicina regenerativa, su amplio espectro ha permitido la aparición de nuevas técnicas para la generación de andamios de diversos tamaños, formas, con características estructurales únicas capaces de generar e innovar tratamientos nuevos ante enfermedades ...
Juan Sebastián Guerra Villacis, Seqqat Rachid, Christian Patricio Narváez Muño, Marbel Torres Arias   +3 more
openaire   +2 more sources

Topology‐Encoded Charge Polarity Governs Multiphase Organization in Intrinsically Disordered Protein Polymer Condensates

Small, EarlyView.
Electrostatic topology is shown to program phase separation and internal organization in thermoresponsive intrinsically disordered protein polymer (IDPP) condensates. By comparing oppositely charged IDPPs with a covalent diblock, chain connectivity is revealed to control charge compensation, dense‐phase micropolarity, miscibility, and apparent acid ...
Julio Fernández‐Fernández, Vicente Domínguez‐Arca, Raúl Escribano, Sheila Lorenzo, Sergio Ferrero, Sergio Acosta, José Carlos Rodríguez‐Cabello   +6 more
wiley   +1 more source

Lost in Translation: Why Biologic Therapies for Intervertebral Disc Degeneration and Low Back Pain Have Not Reached the Clinic (Yet)

JOR SPINE, Volume 9, Issue 3, September 2026.
From preclinical promise to clinical translation in intervertebral disc degeneration (IDD). Robust preclinical evidence supports a range of biologic therapies, with consistent improvements in imaging, extracellular matrix composition, inflammation, and behavior.
Luca Ambrosio, Jordy Schol, Clara Ruiz‐Fernandez, Vincenzo Denaro, Gianluca Vadalà, Daisuke Sakai   +5 more
wiley   +1 more source