Results 41 to 50 of about 169,494 (250)

Impact of transient down-regulation of DREAM in human embryonic stem cell pluripotency

open access: yesStem Cell Research, 2016
Little is known about the functions of downstream regulatory element antagonist modulator (DREAM) in embryonic stem cells (ESCs). However, DREAM interacts with cAMP response element-binding protein (CREB) in a Ca2+-dependent manner, preventing CREB ...
A. Fontán-Lozano   +6 more
doaj   +1 more source

Técnicas del futuro: ingeniería de tejidos y uso de células madre en medicina reproductiva

open access: yesRevista Médica Clínica Las Condes, 2010
Últimamente ha cobrado gran interés en la comunidad médica y científica, el avance experimentado por la medicina regenerativa, la ingeniería de tejidos y el uso de terapias celulares en base a células autólogas maduras, como también el uso de células ...
V. Cecilia Fabres, Dra.
doaj   +1 more source

Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency

open access: yesNature Communications, 2020
The ATM kinase is a key regulator of the DNA damage response to double-strand breaks (DSBs) and its homozygous loss in patients predisposes to lymphoid malignancies.
Alejandro Álvarez-Quilón   +10 more
doaj   +1 more source

Bioinductive collagen implants facilitate tendon regeneration in rotator cuff tears

open access: yesJournal of Experimental Orthopaedics, 2022
Purpose To evaluate the clinical outcomes, MRI imaging and histological characteristics of biopsy samples of the tendon from patients in whom rotator cuff repair was previously performed with a bioinductive type I bovine collagen implants.
Jorge Alberto Camacho‐Chacon   +6 more
doaj   +1 more source

Temporomandibular joint regeneration: proposal of a novel treatment for condylar resorption after orthognathic surgery using transplantation of autologous nasal septum chondrocytes, and the first human case report

open access: yesStem Cell Research & Therapy, 2018
Background Upon orthognathic mandibular advancement surgery the adjacent soft tissues can displace the distal bone segment and increase the load on the temporomandibular joint causing loss of its integrity.
Ricardo de Souza Tesch   +11 more
doaj   +1 more source

DNA-RNA hybrids at DSBs interfere with repair by homologous recombination

open access: yeseLife, 2021
DNA double-strand breaks (DSBs) are the most harmful DNA lesions and their repair is crucial for cell viability and genome integrity. The readout of DSB repair may depend on whether DSBs occur at transcribed versus non-transcribed regions.
Pedro Ortega   +4 more
doaj   +1 more source

Técnicas de medicina veterinária integrativa na FMV Universidade Lusófona

open access: yes, 2022
A medicina veterinária integrativa (MVI) incorpora os aspectos eficazes dos cuidados usuais, também denominados de convencionais ou tradicionais, com os complementares para conseguir o melhor estado de saúde para os pacientes.
Leme, Fabíola   +7 more
core  

BRCA1 Accelerates CtIP-Mediated DNA-End Resection

open access: yesCell Reports, 2014
DNA-end resection is a highly regulated and critical step in the response and repair of DNA double-strand breaks. In higher eukaryotes, CtIP regulates resection by integrating cellular signals via its posttranslational modifications and protein-protein ...
Andrés Cruz-García   +2 more
doaj   +1 more source

Biopolímeros: Aplicaciones de andamios en medicina regenerativa

open access: yesAnatomía Digital, 2021
Los biopolímeros se han convertido en un herramienta indispensable para el desarrollo de la medicina regenerativa, su amplio espectro ha permitido la aparición de nuevas técnicas para la generación de andamios de diversos tamaños, formas, con características estructurales únicas capaces de generar e innovar tratamientos nuevos ante enfermedades ...
Juan Sebastián Guerra Villacis   +3 more
openaire   +2 more sources

Avances en medicina regenerativa [PDF]

open access: yes, 2017
Además de los autotrasplantes de médula ósea para tratamiento de leucemias y de piel para regeneración de quemaduras, existen nuevas técnicas y avances clínicos muy recientes en medicina regenerativa.
Coll Morales, Julio
core  

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