Results 41 to 50 of about 782,998 (207)

Decidualized human decidual stromal cells inhibit chemotaxis of activated T cells: a potential mechanism of maternal-fetal immune tolerance

open access: yesFrontiers in Immunology, 2023
BackgroundNumerous lines of evidence confirm that decidual stromal cells (DSCs) play a key role in maternal–fetal immune tolerance. Under the influence of progesterone and other hormones, the DSCs go through a process of differentiation (decidualization)
Tatiana Llorca   +11 more
doaj   +1 more source

Radiobiology studies of gold nanoparticle‐enhanced radiosensitization in proton therapy

open access: yesMedical Physics, Volume 53, Issue 8, August 2026.
Abstract Background Approximately 50%$\%$ of newly diagnosed cancer patients worldwide receive radiotherapy, most commonly with X‐rays. Proton therapy has emerged as a promising alternative, offering complementary advantages over conventional X‐rays due to its highly localized energy deposition at the Bragg peak, thereby reducing radiation exposure to ...
N. Fuster‐Martínez   +13 more
wiley   +1 more source

TGF-β-Upregulated Lnc-Nr6a1 Acts as a Reservoir of miR-181 and Mediates Assembly of a Glycolytic Complex

open access: yesNon-Coding RNA, 2022
Long non-coding RNAs (lncRNAs) have emerged as key regulators in a wide range of biological processes. Here, we identified a mouse miRNA-host gene lncRNA (Lnc-Nr6a1) upregulated early during epithelial-to-mesenchymal transition (EMT).
Salvador Polo-Generelo   +6 more
doaj   +1 more source

Biomimetic Collagen Scaffolds Natural Cross‐Linking Strategies via Transglutaminase and Methylglyoxal for Skin Repair

open access: yesJournal of Biomedical Materials Research Part A, Volume 114, Issue 7, July 2026.
ABSTRACT Collagen‐based scaffolds are widely used in tissue engineering for skin repair due to their biocompatibility and structural resemblance to extracellular matrix. However, rapid degradation and insufficient mechanical stability limit their effectiveness. This study investigates natural cross‐linking strategies utilizing Transglutaminase (TG) and
Mina Vaez   +6 more
wiley   +1 more source

Las células mesenquimales y sus vesículas extracelulares. Una propuesta alterna en el manejo inmunoregulador y regenerativo en pacientes con psoriasis

open access: yesRevista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica
La psoriasis es una enfermedad crónica inflamatoria que afecta el 2 a 3 % de la población mundial, se produce por una activación anormal del sistema inmune principalmente por las vía IL23 / Th17 y la IL12 /Th1 generando una hiperproliferación de los ...
Luz Mabel Avila Portillo   +2 more
doaj   +1 more source

Both CD133 Cells and Monocytes Provide Significant Improvement for Hindlimb Ischemia, Although They do not Transdifferentiate Into Endothelial Cells

open access: yesCell Transplantation, 2010
To address a number of questions regarding the experimental use of bone marrow (BM) stem cells in hindlimb ischemia, including which is the best cell type (e.g., purified hematopoietic stem cell or monocytes), the best route of delivery [intramuscular ...
Fermin M. Sanchez-Guijo M.D., PhD.   +11 more
doaj   +1 more source

Role of the YAP/TAZ-TEAD Transcriptional Complex in the Metabolic Control of TRAIL Sensitivity by the Mevalonate Pathway in Cancer Cells

open access: yesCells, 2023
Different studies have reported that inhibiting the mevalonate pathway with statins may increase the sensitivity of cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), although the signaling mechanism leading to this ...
Younes El Yousfi   +3 more
doaj   +1 more source

Suero autólogo ¿Medicina regenerativa en Oftalmología? [PDF]

open access: yes, 2017
La presente revisión abarca el uso del suero autólogo en la oftalmología. Se revisaron las propiedades, indicaciones de su uso sobre la superficie ocular, sus efectos biológicos, los efectos adversos que podrían aparecer así como las contraindicaciones ...
Parapar Tena, Sol Ines   +3 more
core  

Personalized Cancer Vaccines in the Clinical Trial Pipeline

open access: yesAsia-Pacific Journal of Clinical Oncology, Volume 22, Issue 3, Page 362-368, June 2026.
ABSTRACT Aim To present an overview of personalized cancer vaccines currently undergoing clinical development, aiming to enhance awareness and promote collaboration among academic, commercial researchers, and non‐profit communities. Methods A dataset of 78 clinical trials for personalized cancer vaccines was generated using ClinicalTrials.gov database ...
Liudmila Iamukova, Elena Alferova
wiley   +1 more source

Human predecidual stromal cells are mesenchymal stromal/stem cells and have a therapeutic effect in an immune-based mouse model of recurrent spontaneous abortion

open access: yesStem Cell Research & Therapy, 2019
Background Human decidual stromal cells (DSCs) are involved in the maintenance and development of pregnancy, in which they play a key role in the induction of immunological maternal–fetal tolerance.
Raquel Muñoz-Fernández   +8 more
doaj   +1 more source

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