Results 61 to 70 of about 324,334 (253)

Cannabis use and mania symptoms : a systematic review and meta-analysis [PDF]

, 2014
Background: Whilst cannabis use appears to be a causal risk factor for the development of schizophrenia-related psychosis, associations with mania remain relatively unknown.
Marwaha, Steven, Singh, SP, Marwaha, S, Gilbert, E, Broome, Matthew, Singh, Swaran P, Broome, M, Gilbert, Eleanor, Singh, Swaran P., Broome, Matthew R., Gibbs, Melanie, Marwaha, Steven; id_orcid, Winsper, Catherine, Gibbs, M, Winsper, C   +14 more
core   +1 more source

Changes in effectiveness and safety in patients with Lennox–Gastaut syndrome transitioning from the fenfluramine randomized controlled trial to open‐label extension study

Epilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis describing the trajectories of fenfluramine effectiveness and safety, along with dose changes over time, in patients with Lennox‐Gastaut syndrome. Abstract In the phase 3 randomized controlled trial (RCT; NCT03355209) of fenfluramine in Lennox–Gastaut syndrome (LGS),
Rima Nabbout, Orrin Devinsky, Lieven Lagae, Ingrid E. Scheffer, Renzo Guerrini, Joseph Sullivan, Antonio Gil‐Nagel, Sameer M. Zuberi, Kate Riney, Patrick Healy, Jayne Abraham, Rebecca Zhang Roper, Mélanie Langlois, Amélie Lothe, Kelly G. Knupp   +14 more
wiley   +1 more source

Medicinal cannabis: knowledge, beliefs, and attitudes of Colombian psychiatrists

Journal of Cannabis Research, 2021
Background The use of cannabinoids in mental health has gained strength in recent years due to emerging scientific evidence and the lifting of prohibitionist laws that prevailed for years in many countries, including Colombia.
Juan Manuel Orjuela-Rojas, Xiomara García Orjuela, Sabina Ocampo Serna   +2 more
doaj   +1 more source

Efficacy and safety of fenfluramine in Dravet syndrome: The impact of patient clinical characteristics

Epilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis evaluating the efficacy and safety of fenfluramine in patients with Dravet syndrome stratified by age, number of previously attempted antiseizure medications, and SCN1A pathogenic variant status using data pooled from the three pivotal randomized controlled trials ...
Rima Nabbout, Joseph Sullivan, Stéphane Auvin, J. Helen Cross, Orrin Devinsky, Antonio Gil‐Nagel, Renzo Guerrini, Kelly G. Knupp, M. Scott Perry, Rocío Sánchez‐Carpintero, An‐Sofie Schoonjans, Ingrid E. Scheffer, Nicola Specchio, Adam Strzelczyk, James Wheless, Elaine C. Wirrell, Diego Morita, Patrick Healy, Mélanie Langlois, Amélie Lothe, Lieven Lagae   +20 more
wiley   +1 more source

La regulación del cannabis medicinal en el Ecuador frente a la tutela del derecho humano al acceso al medicamento ¿es la mercantilización la única opción?

, 2018
La evidencia médico-científica, histórica y empírica relacionada al uso del cannabis con fines terapéuticos, ha representado hasta la actualidad una base sostenible mediante la cual el derecho ha cuestionado y rebatido la prohibición y desregulación de ...
Mora Bassante, Jhon Esteban
core   +1 more source

Advancing Gel Systems with Natural Extracts: Antioxidant, Antimicrobial Applications, and Sustainable Innovations

Gels
The integration of natural extracts into gel systems has emerged as a transformative approach to enhance functional properties, including antioxidant, antimicrobial, and therapeutic effects.
Arthitaya Kawee-ai
doaj   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

The Role of Medicinal Cannabis as an Emerging Therapy for Opioid Use Disorder

Pain and Therapy
This narrative review explores current insights into the potential use of medicinal cannabis-related products as an emerging therapy for opioid use disorder in the landscape of increasing knowledge about medicinal cannabis-based products ...
Kelvin Le, Khang Duy Ricky Le, Johnny Nguyen, Jean Hua, Sarah Munday   +4 more
doaj   +1 more source

The regulatory and scientific context in the study of the medicinal use of cannabis in Peru

Frontiers in Medicine
Cannabis has been historically utilized for medicinal purposes worldwide. However, it was classified as a controlled substance under the United Nations’ 1961 Single Convention on Narcotic Drugs, alongside coca and opium.
Pedro Wong-Salgado, Pedro Wong-Salgado, Jeel Moya-Salazar, Hans Contreras-Pulache, Claudio Pardo-Villarroel, Claudio Pardo-Villarroel   +5 more
doaj   +1 more source

Adolescent Withdrawn/Depressed Symptoms: A Pathway From Early Adversity to Later Marijuana Use

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Adverse childhood experiences (ACEs) are robust predictors of marijuana use, yet the developmental mechanisms remain unclear. Building on prior cross‐sectional studies using broad internalizing composites, this study prospectively distinguishes withdrawn/depressed from anxious/depressed symptoms as candidate mediators across ...
Mahsa P. Yousefkhani, Sara A. Vasilenko, Rachel A. Razza   +2 more
wiley   +1 more source